Category: JCN Newswire

Raleigh, North Carolina and Zurich, September 4, 2025 - (JCN Newswire via SeaPRwire.com) - Hitachi Energy, a wholly owned subsidiary of Hitachi, Ltd., and global leader in electrification, today announced a historic investment of more than $1 billion USD to expand the production of critical electrical grid infrastructure in the United States. These investments, among the largest seen in the electrical industry in the U.S., include approximately $457 million USD for a new large power transformer facility in South Boston, Virginia, along with significant expansions of existing facilities throughout the country.Aeiral photo of Hitachi Energy’s South Boston, VA campusThe investments will help meet skyrocketing energy demand driven by AI data centers in line with the Trump Administration’s White House AI Action Plan and promote domestic access to these critical grid technologies. This move also supports the power needs of American manufacturing and other sectors and much-needed grid expansion and modernization efforts. Collectively, these investments will create thousands of jobs, bolster electrical equipment supply chains in the U.S., and contribute to the development of innovative technologies to enhance the security and resilience of the U.S. grid.“If we are going to win the AI race, reindustrialize, and keep the lights on, America is going to need a lot more reliable energy,” said Energy Secretary Chris Wright. “Thankfully, Hitachi is delivering. The Trump administration looks forward to continuing to partner with private industry to ensure the American people access to affordable, reliable, and secure energy and thousands of high-paying jobs."“To lead in AI, America must lead in energy, and this investment proves we’re doing just that,” said Secretary of the Interior Doug Burgum. “Hitachi Energy’s historic investment in U.S. grid infrastructure is more than a single partnership, it signals a growing wave of investment in American energy. This momentum is driven by President Donald Trump's bold, pro-energy policies that are reigniting the American economy and powering the next generation of critical AI data centers with reliable, American-made energy."“Prioritizing domestic production of transformers accelerates President Trump’s energy dominance agenda by fortifying critical supply chains, strengthening U.S. energy security, and ensuring our nation can meet the growing energy demand. Investments like this are essential to powering AI infrastructure and advancing President Trump’s leadership in the global AI race,” said Jarrod Agen, Executive Director of the White House National Energy Dominance Council.“Thank you, Hitachi Energy, for trusting Virginia, again! Hard-working Virginians and a business friendly environment are what first brought Hitachi Energy to the Commonwealth. Now, after years of success here, they are doubling down on that decision with this landmark investment in South Boston,” said Governor Glenn Youngkin. “Eight-hundred and twenty-five new jobs will be transformational for Southside Virginia, as will the power transformers those new hires are set to build. These transformers are critical to our Nation’s electrical grid and will be built right there in Virginia.” Governor Youngkin continued: “We are also proud to announce a major workforce housing project to support Hitachi’s new employees. We are partnering with Halifax County and Virginia Housing to build 96 new homes supported by a grant from the Virginia Workforce Housing Investment Program.”“Particularly at this critical moment for our growing energy demands, I’m excited to see Hitachi Energy expand their Virginia footprint, create hundreds of good-paying jobs in South Boston, and promote American energy security,” said U.S. Senator Mark Warner. “At the local level, this is a great investment in Southside Virginia’s economy and manufacturing industry. At the state and national level, this is an important strategic step to ensure we have the power needed to service our communities, businesses, and growing AI industry. I’m thrilled to see Hitachi Energy bring this important project home to South Boston.” “In August, I visited Hitachi’s facility in Bland to learn about the company’s cutting-edge work. I’m thrilled that Hitachi Energy is expanding its footprint in Virginia by investing $457 million to build a state-of-the-art power transformer facility in South Boston – creating more than 800 jobs and boosting the region’s economy,” said U.S. Senator Tim Kaine. “Virginia’s workforce, educational opportunities, and innovative spirit have made it a great place to do business, and I look forward to continuing to partner with Hitachi to boost domestic manufacturing in the Commonwealth.”“A vigorous and reliable electric grid is critical for the American economy and American energy dominance. Bringing power transformer production to the U.S. is vital as energy demand skyrockets,” said Congressman John McGuire (VA-05). “I am thankful that this investment will establish a state-of-the-art manufacturing facility in South Boston, to produce necessary large power transformers. This $457 million investment and facility will create more than 800 new high-paying jobs in Virginia’s Fifth Congressional District. I would like to thank Hitachi, President Trump, and Governor Youngkin for working with me to make this a success.”"The United States is a key market for Hitachi, and this investment reflects our commitment to powering America's energy future to meet the accelerating demands for reliable and sustainable solutions to benefit the nation. Leveraging our expertise in IT, operational technology, and advanced products, we are supporting American manufacturing, the development of critical infrastructure, and the rapid expansion of data centers driven by AI adoption," said Toshiaki Tokunaga, President & CEO of Hitachi.“Power transformers are a linchpin technology for a robust and reliable electric grid and winning the AI race. Bringing production of large power transformers to the U.S. is critical to building a strong domestic supply chain for the U.S. economy and reducing production bottlenecks, which is essential as demand for these transformers across the economy is surging. As the global leader in electrification Hitachi Energy is uniquely positioned to deliver critical power solutions for the American market,” said Andreas Schierenbeck, CEO of Hitachi Energy. “Our investments in expanding U.S. transformer manufacturing capacity—including at our new South Boston facility—are already creating good-paying American jobs, strengthening local communities, and reinforcing economic independence. At Hitachi Energy, we are deeply grateful for the leadership and support of the Trump administration, Governor Youngkin, Virginia’s General Assembly, and the Commonwealth’s congressional delegation, who came together to make this critical production capacity possible to power our energy future.”Central to this investment plan is the establishment of a state-of-the-art manufacturing facility in South Boston, Virginia, to produce large power transformers, which support applications like high-voltage transmission, power generation, AI data centers, and large-scale industrial applications. This facility will be built alongside Hitachi Energy’s existing campus and will be the largest manufacturing site for large power transformers in the United States. This facility alone will create more than 825 new jobs in Southside Virginia, offering long-term employment opportunities in engineering, advanced manufacturing, and operations roles. These projects are part of a more than $9 billion USD global investment program, the largest in the industry, under which Hitachi Energy is expanding its manufacturing capacity, R&D, engineering, and partnerships to power the world’s energy system to be more reliable, secure, and resilient.About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT (Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries – and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024(ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at https://www.hitachi.com.About Hitachi EnergyHitachi Energy is a global technology leader in electrification, powering a sustainable energy future with innovative power grid technologies with digital at the core. Over three billion people depend on our technologies to power their daily lives. With over a century in pioneering mission-critical technologies like high-voltage, transformers, automation, and power electronics, we are addressing the most urgent energy challenge of our time – balancing soaring electricity demand, while decarbonizing the power system. With an unparalleled installed base in over 140 countries, we cocreate and build long-term partnerships across the utility, industry, transportation, data centers, and infrastructure sectors. Headquartered in Switzerland, we employ over 50,000 people in 60 countries and generate revenues of around $16 billion USD. https://www.hitachienergy.comhttps://www.linkedin.com/company/hitachienergyhttps://x.com/HitachiEnergy Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, September 5, 2025 - (JCN Newswire via SeaPRwire.com) — NEC Corporation (NEC; TSE: 6701) participated in Locked Shields 2025, an international cyber defence exercise organised by the NATO Cooperative Cyber Defence Centre of Excellence (CCDCOE). NEC also supported design and construction of the exercise environment for the team from Japan, including its network and analysis infrastructure.Locked Shields has been organized by the CCDCOE since 2010 and is one of the world's largest cyber defence exercises. This year, it was held from 6-9 May and involved approximately 40 countries, including NATO member states. The Japanese contingent included representatives from government agencies, including the Ministry of Defense, as well as private sector companies and others. Participating countries were divided into 17 teams, with the delegation from Japan forming a joint team with the delegation from Australia.The exercise aims to improve the ability to deal with cyber-attacks in real-time. It provides training in practical cyber defence and strategic decision-making, including technical and legal responses to complex and simultaneous cyber incidents under realistic scenarios.NEC has enhanced its technical capabilities through the use of the latest cyber security technologies and the accumulation of practical experience, including the provision of cyber security exercises and training, which contributes to strengthening Japan's economic security and the defence of critical infrastructure.NEC will establish a Cyber Intelligence & Operation Centre in Japan this October, which will provide services to the Japanese Government, critical infrastructure providers, and Japanese companies operating internationally.Going forward, NEC will continue contributing to the support of a safe and secure society by helping to ensure economic security through advanced cyber security services.About NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com. Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Sept 5, 2025 - (JCN Newswire via SeaPRwire.com) - TANAKA PRECIOUS METAL GROUP Co., Ltd. (Head office: Chuo-ku, Tokyo; Group CEO: Koichiro Tanaka) announces that its Board of Directors tentatively decided, at a meeting held on August 22, 2025, the appointment of executives for TANAKA PRECIOUS METAL GROUP Co., Ltd., TANAKA PRECIOUS METAL TECHNOLOGIES Co., Ltd., TANAKA PRECIOUS METAL RETAILING Co., Ltd., TANAKA ELECTRONICS Co., Ltd., and EEJA Ltd.TANAKA PRECIOUS METAL GROUP Co., Ltd.TANAKA Corporate Websitehttps://www.tanaka.co.jp/english/Press inquiriesTANAKA PRECIOUS METAL GROUP Co., Ltd.https://www.tanaka.co.jp/support/req/other_contact_e/index.htmlPress Release: https://www.acnnewswire.com/docs/files/20250904.pdf TANAKA’s Executive Appointments Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, September 4, 2025 - (JCN Newswire via SeaPRwire.com) – Honda Motor Co., Ltd. (Honda) will begin sales in Japan of the all-new Prelude tomorrow, on September 5, 2025.Inspired by the image of gliders soaring freely and boundlessly through the open sky, Honda developed the all-new Prelude under the grand concept of “Unlimited Glide,” striving for a vehicle that evokes the uplifting sensation of gliding gracefully through the air and extraordinary experience that people do not have in their everyday lives. Equipped with a further advanced e:HEV, original Honda hybrid system, this model will become the “prelude” for future Honda specialty sports models in the electrified era.All-new PreludeAll-new Prelude information website: https://www.honda.co.jp/PRELUDE/ (Japanese)Sales plan (monthly, in Japan): 300 unitsKey features of all-new PreludeExterior designThe all-new Prelude features a low, sharp front nose and smooth, yet expressive body lines, which contribute to the uplifting sensation of gliding through the air, as well as a low and wide stance that evokes a sense of dynamic driving. The headlight design expresses the soaring momentum, consisting of a wing-like multifunction light which features finely molded stripes that ascend outward, as well as Adaptive Driving Beam and Active Cornering Light, which enhances visibility during nighttime driving.Moreover, a smooth and clean roofline was achieved by eliminating roof molding with the use of laser brazing technology to produce the roof and the adoption of a glass-printed antenna. The blue accents at the lower center of the front and rear fascias create an elegant flow and the low and sporty stance of the vehicle, representing the grand concept of “Unlimited Glide.” In addition, the exterior styling features meticulous attention to detail, including the flush outer door handles and a black chrome grille louver.Interior design Design evoking the uplifting sensation of gliding through the air was also applied to the interior of the all-new Prelude, ensuring a comfortable space not only for the driver but the front passenger as well. The front seats were designed differently to suit separate needs: the driver’s seat is shaped to hold the driver firmly in place, making it suitable for sporty driving, while the passenger seat offers comfort together with just the right amount of feeling of being enveloped.The concept of the all-new Prelude was expressed with the main interior color option— two-tone Blue & White — a color coordination with a high contrast of white and deep blue. The interior design evokes a sense of exclusivity through its fine detailing, such as the softly shaded white surface material that makes it irresistible to touch, the embroidered Prelude logo that enhances the joy of ownership, and the door lining designed in consideration of smooth leg movement during ingress and egress.Other unique interior design features, such as a low and horizontally expansive line of sight, a flat-bottom steering wheel, alloy paddle shifters, and full-graphic meters designed exclusively for Prelude, enhance a sense of anticipation for an exceptional driving experience this vehicle can offer.Seat (Blue × White)Package design As a new-generation specialty car that offers new value to the customer, the all-new Prelude features a package design that achieves seemingly conflicting qualities —specialty and versatility. In order to realize the proportions worthy of a specialty sports model with a wide, low and smoothly sculpted body, the ratio of the tire outer diameter to overall vehicle height was set at approximately 50%, which has been the standard for sports cars. The tread-to-wheelbase ratio, which greatly affects dynamic performance of the vehicle, was set to achieve both straight-line stability and high cornering performance, referencing sports models Honda has designed in the past.In addition, a cargo space, with a large liftback opening that makes loading and unloading easy, is spacious enough to accommodate two medium-size suitcases*1. The standard 60/40 split rear seatbacks fold flat to greatly expand the available space, enough to accommodate larger items such as two golf bags with 9.5” top*2 or two surfboards*3. Moreover, the cargo space offers remarkable utility and versatility, featuring an underfloor storage compartment, convenient hooks, and a cargo floorboard that can be folded and held in place to serve as a cargo space divider to separate items in the front and the rear part of the cargo hold.*1 Suitcase below approximate measurements of 440mm (17 inches) in length, 240mm (9.5 inches) in width, and 670 mm (26 inches) in height. Some suitcases may not fit, depending on their shape.*2 Some golf bags may not fit, depending on their shape.*3 Shortboards with lengths below 1920mm (6 feet 3 5/8 inches). Some shortboards may not fit, depending on their shape.Dynamics- Honda S+ Shift: New e:HEV technology that stimulates all of the driver’s sensesAll-new Prelude became the first model equipped with the original Honda e:HEV hybrid system with Honda S+ Shift control technology. The Honda S+ Shift emulates a virtual 8-speed transmission on the motor-driven e:HEV system (which has no mechanical transmission) and precisely controls the engine RPM during acceleration and deceleration to realize direct drive response and sharp gear shifting feel as if the vehicle features a stepped transmission system.Moreover, with the combination of the Active Sound Control (ASC) system, which enhances engine sound quality by offering a powerful engine sound in sync with engine RPM through the speaker system, and other technologies such as a highly responsive meter display system that operates in coordination with ASC, the Honda S+ Shift technology stimulates all of the driver’s senses and provides exhilarating driving at the will of the driver, further “synchronizing” the driver and the vehicle.As a control inspired by the glider — the motif of the development concept — the all-new Prelude features a new Coasting Control for the first time among any Honda vehicle. The Coasting Control allows the vehicle to decelerate as if it were in neutral gear. For example, when the driver releases the accelerator early while approaching a red light, by moving the deceleration selector to (+) while in “D (drive) range,” the need to re-accelerate will be reduced, alleviating driver burden of having to use both the accelerator and brake pedals.Furthermore, the all-new Prelude comes with three distinctive drive modes — Sport, GT and Comfort. By combining with the Honda S+ Shift control which accentuates the respective characteristics of each mode, drivers can enjoy six distinctive driving experiences. In addition, an “Individual” mode is also available, allowing the driver to customize the settings in six areas — powertrain, steering, suspension, meter display, engine sound, and adaptive cruise control — and enjoy driving in their personalized driving style. Honda S+ Shift Drive mode switch- Excellent driving performance as a hybrid vehicleHigh-strength steel was applied extensively to achieve both responsive handling and a smooth ride, and an aluminum front hood was adopted to realize body frames that combine rigidity and flexibility. As to aerodynamic characteristics, close attention was paid to the smallest aerodynamic design details to ensure consistent cornering feel will be achieved in the entire speed range, from low to high speeds.Based on the chassis of the Civic Type R, designed to pursue pure sports performance, the all-new Prelude features dedicated settings to achieve both responsive handling and a smooth ride, achieving a chassis befitting a specialty sports model. Key features include the following:- Dual-axis strut front suspension that delivers exceptional handling and road-hugging performance- Adaptive damper system (ADS) that precisely controls damping forces- High-response steering system that offers high rigidity and excellent handling with VGR*4- Driveshaft with uniform rigidity that suppresses torque steer and enhances steering stability- High-capacity front Brembo brakes that deliver linear braking feel and excellent fade resistance to enhance driver confidence- 19-inch large-diameter, high-rigidity wheels with a noise-reducing designIn addition, the all-new Prelude features the first application among all Honda models, of enhanced Honda Agile Handling Assist, which improves steering responsiveness and stability during cornering, with a newly extended range of application including braking. The enhanced Honda Agile Handling Assist enables seamless line-tracing from turn-in to corner exit, contributing to enhanced stability of vehicle behavior even in difficult situations such as obstacle avoidance.*4 Variable Gear RatioFor more details, please visit: https://global.honda/content/dam/site/global-en/newsroom-new/cq_img/news/2025/09/4250904eng-prelude/4250904eng-prelude.pdf Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Iwakuni City, Yamaguchi Prefecture, September 4, 2025 - (JCN Newswire via SeaPRwire.com) - Mazda Motor Corporation (Mazda) today signed an agreement with Yamaguchi Prefecture and Iwakuni City regarding the construction of the "Mazda Motor Corporation Iwakuni Plant," a new module pack plant for automotive cylindrical lithium-ion battery cells in Iwakuni City, Yamaguchi Prefecture, as announced in January this year. Based on this agreement, construction will commence in November this year, with the aim of starting plant operations in fiscal year 2027. The Iwakuni Plant will be Mazda's first new domestic plant since the start of operations at the Hofu No.2 Plant in 1992.Mazda is promoting electrification through its multi-solution approach to flexibly respond to diversifying customer needs and changing environmental regulations globally. The Iwakuni Plant will play an important role as a foundation supporting the global expansion of electrified products. This plant will assemble modules of automotive cylindrical lithium-ion battery cells sourced from Panasonic Energy Co., Ltd., and package them into battery packs. The plant aims to create a safe, secure, and comfortable workplace, and to contribute to local employment and economic development.Mazda is committed to delivering the "joy of driving" and smiles to customers around the world by incorporating the technology and high quality produced at the Iwakuni Plant into its electric vehicles.New Plant OverviewNameMazda Motor Corporation Iwakuni PlantProductCylindrical Lithium-Ion Battery Packs for Automotive UseProduction CapacityAnnual capacity of 10 GWh at maximumLocation3915 Minamishirazaki, Tsuzu, Iwakuni City, Yamaguchi PrefectureLand AreaApproximately 190,000 m²Construction StartNovember 2025Start of operationsIn Fiscal Year 2027 Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, September 4, 2025 - (JCN Newswire via SeaPRwire.com) — NEC Corporation (NEC; TSE: 6701) today announced that it will begin a proof of concept (PoC) for introducing an Earthquake Early Warning System (EEWS) in Colombia. This follows NEC’s selection to undertake the "Project for Conducting a Feasibility Study on the Introduction of ICT-Based Early Earthquake Detection and Analysis Technology in the Republic of Colombia," for which Japan’s Ministry of Internal Affairs and Communications had issued a public solicitation for proposals.With the ultimate goal of providing an EEWS overseas for the first time, NEC plans to conduct this PoC in Colombia between September 2025 and March 2026 to verify the effectiveness of the EEWS and identify any potential issues.The role of EEWS in earthquake early warningsBackgroundColombia is a seismically active nation located along the circum-Pacific Ring of Fire. Extensive human and material damage were reported following a magnitude 6.2 earthquake in Colombia’s Department of Quindio in January 1999 and another that shook the nation’s capital of Bogota in August 2023 with a magnitude of 6.3. Since then, calls have grown for the establishment of a system to swiftly provide the government and the general public with earthquake information.NEC has a proven track record for reliable operation of its EEWS, which it has been providing for the Japan Meteorological Agency (JMA) since 2007. NEC now seeks to contribute to earthquake preparedness in Colombia with the introduction of a new EEWS.Introduction of EEWSEEWS is a system that calculates the epicenter and magnitude from the initial tremors (P-waves) detected by seismometers, enabling it to warn of strong shaking before the main tremors (S-waves) arrive (though in some cases, it may not arrive in time for the strong shaking). Applications include alerting the public via mass media and mobile phones, automatically shutting down infrastructure, and controlling elevators, thereby contributing to the reduction of human and material damage.PoC overviewLeading up to this PoC, NEC was selected by Japan’s Ministry of Internal Affairs and Communications in the public solicitation for proposals it issued in fiscal year 2024 for the "Project for Conducting a Feasibility Study on the Introduction of ICT-Based Early Earthquake Detection and Analysis Technology in the Republic of Colombia," and conducted a preliminary survey from January to March 2025. In this preliminary survey, NEC input seismometer data from 12 past Colombian earthquakes with a magnitude of 5.0 or larger into EEWS for analysis. This historical earthquake data from Colombia was then run on EEWS to confirm that results predicting the epicenter and magnitude could be produced.Building off this preliminary survey, NEC will be connecting existing seismometers installed in Colombia with EEWS online to conduct real-time analysis of the acquired data in the upcoming PoC.Seismic observation point and epicenter data used in the preliminary surveyScreenshot of EEWS monitorLeveraging the outcomes of this PoC, NEC will move forward with its feasibility study for introducing EEWS in Colombia, aiming to contribute to the improvement of earthquake preparedness in the nation.Related LinkDisaster preparedness: Products & Solutions | NEChttps://www.nec.com/en/global/solutions/disaster-management/index.htmlAbout NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com. Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, September 4, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) announced today that the company will deliver a total of 11 presentations, including clinical data on the selective orexin 2 receptor agonist (OX2R)E2086 and the latest findings on its in-house discovered orexin receptor antagonist lemborexant (product name: DAYVIGO®) at the World Sleep Congress (World Sleep 2025) to be held in Singapore from September 5 to 10.Key presentations include results from the Phase Ib clinical study exploring the efficacy (Proof of Mechanism) of E2086 in people diagnosed with narcolepsy type 1 (NT1) and the Phase IV clinical study(SELENADE Study) investigating the effect of lemborexant in people whose insomnia was comorbid with depressive episodes of major depressive disorder and bipolar disorder (Poster 3-133). The company will also host a symposium introducing the latest evidence on lemborexant in Asia.Eisai considers neurology, including sleep disorders such as insomnia and narcolepsy, as a therapeutic area of focus. Eisai strives to create innovative products in therapeutic areas with high unmet medical needs as soon as possible, and will further contribute to addressing the diverse needs of, as well as increasing the benefits provided to, those living with neurological diseases and their families.For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202561pdf.pdf Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, September 3, 2025 - (JCN Newswire via SeaPRwire.com) – Honda today presented the world premiere of four large-size outboard motors, BF350, BF250, BF225 and BF200, featuring a new “Sporty White” color option at the HISWA te Water (HISWA in-water Boat Show) now underway (Sept. 3–7, 2025) in Lelystad, the Netherlands. All four models with the new Sporty White color option will go on sale in Europe today, Sept. 3, and the BF350 and BF250 will go on sale in Japan on Sept. 4, 2025.BF350 in new Sporty White color (installation sample)Based on the already-available “Grand Prix White” color, the new Sporty White color option features a black stripe that creates a two-tone color scheme, achieving distinctive styling with a sense of exclusivity. Since it was first adopted in 2019 for the previous version of the BF250, the Sporty White color scheme has been well received by many customers enjoying marine recreation, particularly in Europe and Japan, for its impressive graphics and sporty design.The new Sporty White color option added this time for the four large-size outboard motors inherits the original design concept of expressing a racing image, while achieving coloring that is perfectly compatible with the refreshed, simple and clean styling design of the motors. By combining the prominent vertical display of the horsepower rating with the red Honda logos positioned on both sides, the design expresses Honda racing DNA, emphasizing both sportiness and a sense of premium quality.The BF350, the flagship model of Honda outboards that went on sale first in Japan in February 2024, is equipped with a V8 350-horsepower engine designed exclusively for this outboard motor to deliver powerful propulsion performance. The all-new BF250, BF225 and BF200, which went on sale first in Japan in May 2025, feature a refreshed styling design aligned with the design concept of BF350. With excellent fuel efficiency and outstanding durability, these Honda outboard motors are used for a wide range of purposes such as fishing and marine leisure.Official website of the HISWA te Water 2025 (HISWA in-water Boat Show)https://www.hiswatewater.nl/ Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Toyota City, Japan, September 3, 2025 - (JCN Newswire via SeaPRwire.com) - Toyota Motor Corporation (Toyota) announced today that it has joined "TOKYO H2," a new project launched by the Tokyo Metropolitan Government on September 3 aiming to make Tokyo a global leader in hydrogen. As part of this public-private initiative, the Crown has been introduced into the fuel cell taxi fleet to expand adoption.The Crown combines the exceptional quietness unique to a fuel cell vehicle (FCEV) with spacious rear seating and excellent ease of entry and exit, delivering comfortable and a premium travel experience unmatched by conventional taxis.To achieve the Tokyo Metropolitan Government's target for introducing fuel cell taxis (approximately 600 by fiscal year 2030), Toyota will also aim to introduce 200 units by fiscal year 2025 and provide support.To coincide with the project's launch, Toyota has renovated and reopened the TOYOTA MIRAI Showroom in Minato City, Tokyo originally established in 2015 as an information center on fuel cell vehicles (FCEVs) and hydrogen as the TOKYO H2 HUB. The new facility will serve as a hub for collaboration among companies and organizations working toward a hydrogen society, contributing to the project's advancement and to the broader adoption of hydrogen energy.TOKYO H2 project logoThe TOKYO H2 project, led by the Tokyo Metropolitan Government, aims to accelerate public―private efforts to use hydrogen, with a focus on commercial mobility such as fuel cell taxis and trucks. Participating companies and organizations will implement a variety of hydrogen-related initiatives. By unifying the project's logo and design, the spread of hydrogen is being made visible throughout the city, raising understanding and interest across Tokyo. Going forward, in addition to taxis, initiatives in the commercial sector will be rolled out in stages.Toyota supports the Tokyo Metropolitan Government's commitment to advancing the social implementation of hydrogen. By introducing the Crown to the fuel cell taxi fleet, Toyota aims to make the hydrogen society more familiar and accessible in everyday life. In addition, by generating substantial hydrogen demand, Toyota seeks to create a virtuous cycle across the supply chain. Working together with the Tokyo Metropolitan Government and with companies and organizations engaged in hydrogen, Toyota will continue to expand partnerships and contribute to realizing a Tokyo that leads the world with hydrogen.Toyota positions hydrogen as an important energy source and, together with many partners, is advancing a wide range of initiatives to promote its use across all areas-producing, transporting, storing, and using. Going forward, Toyota will continue to accelerate efforts to expand the use of hydrogen and contribute to the realization of a hydrogen society.Fuel cell taxi Crown (FCEV)"Achieving zero, and adding new value beyond it"As part of efforts to pass our beautiful "Home Planet" to the next generation, Toyota has identified and is helping to solve issues faced by individuals and overall society, which Toyota calls "Achieving Zero," hoping to help reduce the negative impacts caused by these issues to people and the environment to zero. Additionally, Toyota is also looking "Beyond Zero" to create and provide greater value by continuing to diligently seek ways to improve lives and society for the future.About Beyond Zero https://global.toyota/en/mobility/beyond-zero/Toyota Motor Corporation works to develop and manufacture innovative, safe and high-quality products and services that create happiness by providing mobility for all. We believe that true achievement comes from supporting our customers, partners, employees, and the communities in which we operate. Since our founding over 80 years ago in 1937, we have applied our Guiding Principles in pursuit of a safer, greener and more inclusive society. Today, as we transform into a mobility company developing connected, automated, shared and electrified technologies, we also remain true to our Guiding Principles and many of the United Nations' Sustainable Development Goals to help realize an ever-better world, where everyone is free to move.SDGs Initiatives https://global.toyota/en/sustainability/sdgs/ Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, September 3, 2025 - (JCN Newswire via SeaPRwire.com) – Honda Motor Co., Ltd. (Honda) today announced that a member of the Honda Running Team, Nagiya Mori, has been named to represent Japan in the men’s 5000m event at the World Athletics Championships Tokyo 25 (WCH Tokyo 25), in Tokyo, September 13–21, 2025.Since joining Honda in 2022, Mori has steadily improved his competitive performance. This season, he has been demonstrating his competitive toughness, recording the second-fastest time ever by a Japanese runner in the men’s 3000m event at the Seiko Golden Grand Prix held in May. Later that month, at the Asian Athletics Championships held in Korea, he earned a bronze medal by competing strongly against some of Asia’s top runners. Building on these achievements, Mori secured a berth at the WCH Tokyo 25. In this first opportunity to face world-level competition, he will boldly take on the challenge of competing against the world’s top-class runners.At the WCH Tokyo 25, the men’s 5000m heats are scheduled on Friday, September 19, with the final on Sunday, September 21, 2025, at the Japan National Stadium.As official partner of the WCH Tokyo 25, Honda will provide environmentally-responsible official vehicles, including electric vehicles, based on its theme — “Maximizing the excitement and inspiration from the athletes’ great performance, through the realization of an environmentally-responsible and safe event by providing a wide variety of mobility products equipped with innovative technologies.”Based on the Honda vision for its sports activities – “To increase the number of people who take on challenges through sports activities and make the lives of all people more enjoyable” – Honda will continue to support various athletes who take on challenges toward the realization of their own dreams.Comments by Satoshi Ogawa, Manager of the Honda Running Team“We are very pleased and proud that another member of our team – this time Nagiya Mori, following in the footsteps of Naoki Koyama for the men’s marathon – was selected to represent Japan at the World Athletics Championships Tokyo 25. This will be his first time competing in an international event. We hope he will leverage his natural and outstanding racing instincts and boldly take on the world’s top-class competitors. In order to embody the Honda Challenging Spirit at the pinnacle of a global athletics competition, we will help him prepare for his race with passion and determination. We greatly appreciate your continued support and cheers.”Comments by Nagiya Mori, Honda Running Team Athlete“From my childhood up to now, the thing I’ve loved the most is running and then track and field, which I discovered in my junior high school days. Over time, it became the center of my life. Among my dreams, the one I thought was impossible yet could never give up on was to wear the uniform of the Japan national team and compete at the World Athletics Championships. I am truly happy to have finally realized that dream. I will do everything I can to prepare myself until the day of the race. I would appreciate it if you could cheer me on!”Nagiya Mori Profile Date of Birth: July 3, 1999 (26 years old) Place of Birth: Fukuoka, Japan Teams: Ohori Senior High School Chuo University Honda Running Team Key accomplishments to dateYearEventResult2025109th Japan National Athletics ChampionshipsMen's 5000m2nd26th Asian Athletics ChampionshipsMen's 5000m3rd2024108th Japan National Athletics ChampionshipsMen's 5000m2nd Honda is supporting the World Athletics Championships Tokyo 25, as an Official PartnerReference“Honda Signs Sponsorship Agreement to Provide Electrified Vehicles at World Athletics Championships Tokyo 25”https://global.honda/en/topics/2024/ce_2024-11-07eng.htmlHonda special World Athletics websiteHonda will continuously share its stories and passion for supporting athletes who take on challenges in the WCH Tokyo 25 and introduce a wide variety of Honda vehicles serving active roles during the event.URL: https://global.honda/jp/WorldAthletics/ (Japanese)https://global.honda/en/WorldAthletics/ (English) Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO and CAMBRIDGE, Mass., Sept. 3, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and Biogen Inc. (Nasdaq: BIIB, Corporate headquarters: Cambridge, Massachusetts, CEO: Christopher A. Viehbacher, “Biogen”) announced today that Eisai has initiated the rolling submission of the Supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) for lecanemab-irmb (U.S. brand name: LEQEMBI®) subcutaneous autoinjector(SC-AI), LEQEMBI IQLIK, as a weekly starting dose after the FDA granted Fast Track Status. LEQEMBI is indicated for the treatment of Alzheimer’s disease (AD) in patients with Mild Cognitive Impairment(MCI) or mild dementia stage of disease (collectively referred to as early AD).The sBLA is based on evaluation of subcutaneous (SC) lecanemab administration across a range of doses and as part of sub-studies within the Phase 3 Clarity AD open-label extension (OLE), following the 18-month core study in individuals with early AD. Should the FDA approve the LEQEMBI IQLIK 500mg SC dosing regimen (two 250 mg injections), the autoinjector could be used to administer a once weekly starting dose, as an alternative to bi-weekly (every two weeks) intravenous (IV) dosing. This would expand the option for patients and care partners to receive LEQEMBI treatment from initiation to maintenance at home, offering a choice between IV and SC administration. The current injection time for each LEQEMBI IQLIK autoinjector takes approximately 15 seconds. The SC formulation also has the potential to reduce healthcare resources associated with IV maintenance dosing, such as preparation for infusion and nurse monitoring, while streamlining the overall AD treatment pathwayAD is a progressive, relentless disease with amyloid beta (Aβ) and tau as hallmarks that is caused by a continuous underlying neurotoxic process that begins before amyloid plaque removal and continues afterward.1,2,3 Only LEQEMBI fights AD in two ways – targeting both amyloid plaque and protofibrils*, which can impact tau downstream. LEQEMBI is currently approved in 48 countries and is under regulatory review in 10 countries. Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority.*Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition.1 Protofibrils cause injury to neurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.2 INDICATIONLEQEMBI® is indicated for the treatment of Alzheimer’s disease (AD). Treatment with LEQEMBI should be initiated in patients with mild cognitive impairment (MCI) or mild dementia stage of disease, the population in which treatment was initiated in clinical trials. For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202560pdf.pdf Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Sept 3, 2025 - (JCN Newswire via SeaPRwire.com) - Anime Tokyo Station, an anime exhibition center that utilizes Japanese anime content with a strong fan base around the world, will host the TV anime SPY x FAMILY Special Exhibition from August 16 to November 9, 2025. Ahead of the opening, a press preview was held on August 15.© Tatsuya Endo/Shueisha, SPY x FAMILY Project© Tatsuya Endo/Shueisha, SPY x FAMILY ProjectThe special exhibition will look back on various memorable scenes while exploring the appeal of each character from the series, including Anya. Visitors can enjoy an AR experience where character dialogue appears when they hold up their smartphones, photo spots for taking pictures while being immersed in the world of the series, and other features that allow them to experience the characters’ appeal firsthand.We invite you to visit Anime Tokyo Station and fully enjoy the world of TV anime SPY x FAMILY and the appeal of its characters.What is SPY x FAMILY?In a world of fierce intelligence warfare, the spy “Twilight” receives a mission: create a fake family and attend an elite school’s social gathering to make contact with the target and prevent war with a neighboring country. Twilight assumes the identity of ordinary citizen Loid Forger and assembles a family—but his daughter Anya can read minds, and his wife Yor is a deadly assassin. This hit spy comedy follows a family of secrets striving for world peace.Tatsuya Endo’s original manga began serialization in Shonen Jump+ in March 2019, winning multiple manga awards and surpassing 38 million copies with 15 volumes (as of March 2025).When Season 1 premiered in April 2022, to meet the high expectations of the manga’s fanbase, an unprecedented collaboration was formed between WIT STUDIO and CloverWorks. The production brought together industry-leading talent including director Kazuhiro Furuhashi, as well as popular voice actors Takuya Eguchi, Atsumi Tanezaki, Saori Hayami, and Kenichiro Matsuda, with theme songs by OFFICIAL HIGE DANDISM and Gen Hoshino in the first run of the series, followed by BUMP OF CHICKEN and yama in the second, establishing it as 2022’s breakout anime hit.Season 2 aired from October 2023, bringing the fan-favorite Luxury Cruise Arc from the original work to life on an even grander scale. Ado’s opening theme “Kura Kura” and Vaundy’s ending theme “Todome no Ichigeki (feat. Cory Wong)” became instant sensations.The franchise’s first film, SPY x FAMILY CODE: White, premiered December 22, 2023, with Tatsuya Endo providing the original work, supervision, and character designs. Season 1 director Kazuhiro Furuhashi served as animation advisor, while Season 1 assistant director Takashi Katagiri took the helm. Ichiro Okouchi crafted an entirely original story for the screenplay. Riding the wave of popularity enjoyed by “MIXED NUTS,” OFFICIAL HIGE DANDISM delivered the theme song “SOULSOUP,” with the opening day surprise announcement that Gen Hoshino would perform the ending theme “Why”—reuniting the beloved Season 1 combination to tremendous fan enthusiasm. The film became a blockbuster success, earning 6.26 billion yen and drawing over 4.64 million viewers. With Season 3 set to begin in October 2025 in Japan, anticipation continues to build.Venue Overview- Name: Anime Tokyo Station (also known as "Anime Tokyo")- Location: Floors B1 to 2F of Tokyu East 5 (2-25-5 Minami-Ikebukuro, Toshima-ku, Tokyo)*4 minutes on foot from Ikebukuro Station- Hours: 11:00 a.m. to 7:00 p.m.(last admission: 6:45 p.m. last admission for special exhibitions: 6:30 p.m.)- Closed: Mondays*If Monday falls on a holiday, the venue will be open on Monday and closed on the following dayNew Year's holiday periodMay be closed on other daysPlease check the venue website before coming.- Admission fee: Free- Website: https://animetokyo.jp/en/- SNS:X｜https://x.com/animetokyo_info (@animetokyo_info)Instagram｜https://www.instagram.com/animetokyostation/ (@animetokyostation)YouTube｜https://www.youtube.com/channel/UCSJOjGJE5Yiqw3PZ97AVdJwInquiries regarding this press releasePublic Relations Office of "Anime Tokyo Station" (Kyodo PR)Contact person: Miri YasudaE-mail: animetokyo-pr@kyodo-pr.co.jp Press release: https://www.acnnewswire.com/docs/files/20250903.pdf Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Kawasaki, Japan and San Jose, USA, September 3, 2025 - (JCN Newswire via SeaPRwire.com) - Fujitsu Limited, 1Finity Inc., a Fujitsu company and leading provider of global network solutions, and Arrcus Inc., the hyperscale networking software company and a leader in core, edge, and multi-cloud routing and switching infrastructure, today announced the signing of a strategic partnership contract to strengthen next-generation infrastructure for the AI era and provide innovative network solutions to Japan and the global market.As AI continues to be deployed throughout society and the services available become more sophisticated, AI-related data traffic is increasing exponentially. This trend is driving a growing need for network infrastructure that can seamlessly connect data centers, cloud platforms, 5G/6G networks, and edge environments.Arrcus develops advanced routing and switching platforms based on Ethernet networking technology and provides industry-leading networking software that meets the diverse needs of network operators and enterprise customers.The Network Operating System (OS) software developed by Arrcus can operate in a unified manner across data center clusters, from the edge to multi-cloud environments, enabling faster deployment and centralized management. It does not require dedicated hardware and can run on generic “white box” components, allowing for the placement of white box hardware equipped with the optimal silicon components. Customers that have implemented this software have achieved over 40% reduction in total cost of ownership (TCO) across multiple use cases.Figure 1: Scope of Arrcus Network OS SoftwareUnder this partnership agreement, 1Finity will offer the complete range of Arrcus solutions as its business partner, and will jointly develop go-to-market plans to expand its business globally with a primary focus on Japan, targeting network operators, enterprise customers and data center operators. In addition, the collaboration will extend to business partners on a global scale, not limited to the Fujitsu Group, and build comprehensive total solutions covering network design to maintenance and operation by managed service collaboration to provide optimal value to customers.Fujitsu will leverage its global customer base to provide flexible and scalable solutions that can adapt to rapidly changing market needs, while combining the Arrcus business model with Fujitsu's strengths in AI services and computing technologies to become a next-generation infrastructure service provider for the global market.Shekar Ayyar, Chairman & CEO, Arrcus Inc. comments:“Flexible networks that combine innovation in software, silicon, and optics are of critical importance for AI data centers and 5G/6G connected inference edges. We are super excited to announce our strategic partnership with Fujitsu and 1Finity to bring our combined strengths for Fujitsu internal use as well as for enterprises, service providers, and cloud/neo-cloud operators worldwide.”Masaaki Moribayashi, Corporate Executive Officer, Fujitsu Limited, Representative Director, CEO, 1Finity Inc. comments:“As the amount of AI-related data transfer increases in both volume and complexity, the role of networks has become more important than ever before. Arrcus's products, including its Network OS Software, are innovative and offer exceptional performance which will help us to provide optimal network solutions and meet our customers' needs. We look forward to achieving breakthroughs in networking through this partnership.”Press Conference MaterialsHeld on September 3, 2025Materials from the press conference on Strategic PartnershipAbout FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuAbout 1FINITY1Finity, a Fujitsu company, is a global provider of communications networks for our connected world. We uniquely combine technological leadership and expertise in open optical and wireless networking, network automation, and applied AI/ML to design, build, operate, and maintain critical digital communications network infrastructure. Collaborating closely with ecosystem partners, we deliver transformative outcomes for service providers and network operators, and enable them to lower TCO, improve network performance, and increase energy efficiency. Find out more: www.1Finity.comAbout ArrcusArrcus is a leading provider of networking software solutions that empower businesses to achieve unparalleled scalability, performance, and reliability in their infrastructure. Arrcus is disrupting the industry with disaggregated solutions that deliver innovative, agile, and cost-effective networking, allowing enterprises to break free from traditional, monolithic systems and embrace a more flexible, efficient, and scalable approach to modern networking. The Arrcus team consists of world-class technologists who have an unparalleled record in shipping industry-leading networking products, complemented by industry thought leaders, operating executives, strategic partners, and top-tier VCs. The company is headquartered in San Jose, Calif. Find out more: www.arrcus.com, LinkedIn, Twitter/XPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries1Finity Inc.Susan DiantoE-mail: susan.dianto@fujitsu.comArrcus Inc.Sean GriffinE-mail: sean@arrcus.com Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Massachusetts, USA, September 2, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Corporation ("MC”) is pleased to announce its participation in a third-party allotment of shares by Commonwealth Fusion Systems LLC (Headquarter: Massachusetts, USA, Representative: Bob Mumgaard, “CFS”), a fusion energy start-up originating from MIT *1. This investment was made in collaboration with a consortium of 12 Japanese companies *2 (“Japanese Consortium”). In the field of fusion energy, this investment builds on MC’s previous investment in Kyoto Fusioneering Ltd., announced on May 17, 2023.*1 Massachusetts Institute of Technology*2 MC, Mitsui & Co., Ltd., Kansai Electric Power Co., Inc., JERA, Mitsui O.S.K. Lines, Ltd., JGC, Development Bank of Japan, Inc., NTT Corporation, Fujikura Corporation, Sumitomo Mitsui Banking Corporation, Sumitomo Mitsui Trust Bank, Limited, Mitsui Fudosan Co., Ltd.Fusion energy is produced when two light nuclei, typically deuterium and tritium, collide to form a single heavier nucleus, helium. This is the same process that powers the Sun and other stars. Since no carbon dioxide is emitted during power generation and the fuel is abundantly available in seawater, fusion offers an almost inexhaustible energy source. A small amount of fuel can produce a tremendous amount of energy. Fusion is gaining global attention as a next-generation energy source that supports decarbonization and ensures a stable energy supply. In June 2025, the Japanese government revised its “Fusion Energy Innovation Strategy,” which outlines the development and promotion of fusion energy. This policy aims to position Japan as a global leader in power generation by the 2030s.CFS, a spin-off company of MIT, is the world’s leading and largest private fusion company, utilizing the magnetic confinement system (tokamak type) *3. The company plans to build the world's first commercial fusion power plant "ARC" in Virginia in the United States, with the intent of generating electricity in the early 2030s. In June of this year, CFS announced that it signed a power purchase agreement with Google for 200 megawatts of electricity from its first ARC power plant.The Japanese Consortium will acquire technical and commercial expertise in policy, regulatory, and the development, construction, operation, and maintenance of ARC from CFS's commercialization projects in the United States. In addition, each consortium company will bring together its know-how and expertise and aspire to expedite the commercialization and industrialization of fusion energy power generation in Japan.The collaboration between the Japanese Consortium and CFS is consistent with the Japan – U.S. joint partnership to accelerate the development and commercialization of fusion energy power generation in Japan and the United States, and represents a strong commitment and growing momentum toward the early realization of commercialization in both countries.*3 A torus-shaped fusion energy device that uses a strong magnetic field to confine ultra-high temperature plasmaThrough this investment, MC seeks to acquire cutting-edge knowledge in fusion energy and contribute to both decarbonization and a stable energy supply by leveraging its extensive networks and industrial capabilities to support the practical application of fusion technologies.MaterialityBased on the Three Corporate Principles, which serve as MC’s core philosophy, MC has continued to grow together with society by contributing to the sustainable development of society through its business activities while pursuing value creation. While continuously creating Shared Value guided by the Materiality, a set of crucial societal issues, MC will continue to strengthen its efforts towards sustainable corporate growth. Guided by this Materiality, MC will continue to strengthen its efforts towards sustainable corporate growth. Out of the six material issues relating to “Realizing a Carbon Neutral Society and Striving to Enrich Society Both Materially and Spiritually”, this project’s activities particularly support "Contributing to Decarbonized Societies", “Promoting Stable, Sustainable Societies and Lifestyles” and “Utilizing Innovation to Address Societal Needs”.Inquiry RecipientMitsubishi CorporationTelephone:+81-3-3210-2171 Copyright 2025 JCN Newswire via SeaPRwire.com.

TOKYO, September 2, 2025 - (JCN Newswire via SeaPRwire.com) - Hitachi, Ltd. (TSE:6501, "Hitachi") has been certified as a Gold Partner*1 of Scaled Agile, Inc. ("SAI"), the provider of SAFe®, the world's most trusted system for business agility.SAFe is a management framework that supports organizational transformation and business agility, helping to enhance competitiveness and maximize customer value and is widely adopted globally. Within the Hitachi Group, GlobalLogic was certified as a Silver Partner of SAI in 2021 and has been supporting agile DX transformation based on customer experience.Amid increasingly rapid social change and growing uncertainty, Hitachi will apply SAFe as a common framework across One Hitachi to support customers globally in rapidly adapting to change and continuously creating value. For example, by applying SAFe to the implementation of "HMAX*2", which embodies Lumada 3.0 and aims to solve customer and societal challenges by converting data into value using Hitachi's domain knowledge and AI, Hitachi seeks to accelerate the value delivery cycle.Going forward, through this certification and as part of SAI's official partner network, Hitachi will utilize SAFe as a methodology for enterprise-level agile development. Hitachi will flexibly and continuously support system development management that is aligned with customers' business strategies in response to changes in society and the market environment. Additionally, Hitachi will establish a framework for implementing SAFe within the company and systematically advance human resource development to increase the number of employees with SAFe expertise to 5,000, thereby strengthening practical capabilities and agility.Through these efforts, Hitachi will accelerate social innovation and contribute to the realization of a "Harmonized Society" where environment, wellbeing, and economic growth coexist in harmony.*1 Certification awarded to organizations with five or more certified SAFe consultants (SPCs) who are recognized as capable of leading agile transformations for customers at the enterprise level.*2 September 24, 2024: Hitachi Rail Unveils the ‘HMAX’ AI Solution, Accelerated by NVIDIA, to Optimize Trains, Signaling and Infrastructurehttps://www.hitachi.com/New/cnews/month/2024/09/240924c.htmlBackgroundIn recent years, agile methodologies have become increasingly widespread in system development as companies seek to respond flexibly to uncertain and rapidly changing market environments and strengthen their competitiveness. Hitachi launched its "Agile Development Consulting Service" in 2019 with the aim of providing efficient system development and high-quality IT services. In addition, Hitachi has responded to numerous agile development projects to quickly address changes in our customers' business strategies and market needs, contributing to the enhancement of their experience value. Furthermore, Hitachi has actively worked to improve the speed, flexibility, and scalability of system development by adapting the agile development methodologies used at GlobalLogic for the Japanese market, and applying them to enterprise systems that support the core of business operations. Today, rapid development and service delivery aligned with changes in society and market conditions require organizations to undergo transformation in sync with their corporate strategies.As a result, there is a growing need to leverage proven management frameworks that enhance business agility by flexibly translating those requirements into system development.Future Initiatives1. Strengthening System Development Management Aligned with Customer Business Strategies.Hitachi will leverage SAFe through this partner certification to further accelerate Social Innovation Business by leveraging its strengths in IT, OT, and products. Specifically, we will adopt SAFe, a management framework aligned with business strategy, as a standard methodology for enterprise-level agile system development to enhance business agility. This will enable us to respond flexibly and swiftly to future changes in the business environment, thereby contributing to our customers' sustainable growth and accelerated digital transformation.2. Advancing Human Resource Development.In addition to its framework, SAFe provides certified training courses and agile development coaching for members. Hitachi will utilize these resources to further focus on developing agile human resources, increasing the number of employees with SAFe knowledge to 5,000. Additionally, through Gold Partner certification, Hitachi will gain direct access to the latest insights and training programs from SAI, as well as global best practices from the SAFe partner network worldwide, and will actively utilize these resources.Through these initiatives, Hitachi will systematically establish a framework for SAFe implementation and human resource development within the company, thereby strengthening its practical capabilities and agility from a human resource perspective.Hitachi will continue to promote Social Innovation Business that leverage agile development methods and digital technologies to solve the challenges faced by our customers and society. We will also maximize the knowledge and global network we have cultivated as a SAFe partner to accelerate our customers' DX and contribute to the enhancement of their corporate value.Comments from Phil Knight - VP, Partner Alliances, Scaled Agile, Inc."We are delighted to welcome Hitachi, Ltd. as a Gold Partner in the Scaled Agile Partner Network. By leveraging SAFe® to drive enterprise-wide agile transformation and applying it to their platforms and solutions, Hitachi will further maximize customer value creation. Through this partnership, we look forward to accelerating the adoption of business agility across Japan more than ever before."About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT(Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries –and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024(ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at www.hitachi.com.Business ContactProject Management DivisionDigital Systems & Services Business ManagementDivisionDigital Systems & Services Business DivisionHitachi, Ltdspc-info@ml.itg.hitachi.co.jp Copyright 2025 JCN Newswire via SeaPRwire.com.

KARIYA, JAPAN, September 1, 2025 - (JCN Newswire via SeaPRwire.com) - DENSO CORPORATION (hereinafter “DENSO”) today announced that its Board of Directors has resolved to transfer its Spark Plug and Exhaust Gas Sensor business (Oxygen Sensor and Air-Fuel Ratio Sensor), to Niterra Co., Ltd (hereinafter “Niterra”). The two parties reached a decision to sign the business transfer agreement during a board of directors meeting on September 1st, 2025.In the process of achieving a carbon neutral society, electrified vehicles are expected to become more widespread throughout the auto industry. At the same time, powertrain diversification is expected to continue progressing, in response to differing energy and fuel needs across regions and countries. In such market environment changes, DENSO recognizes that advancing product innovation across all domains and establishing a sustainable supply framework aligned with the anticipated market scale, are challenges for the entire auto industry.Under all these factors, on July 10, 2023, DENSO completed an MOU* to transfer business operations for select internal combustion engine parts to Niterra, which boasts some of the world’s leading technologies in its field.Since then, through extensive discussions and deliberations, the two parties reached an agreement on the business transfer. This decision was made while sharing a common understanding of a strong commitment to the technology and quality of Spark Plug and Exhaust Gas Sensor. Through this transfer, both companies will enhance the product capabilities of internal combustion engines, by integrating technologies and manufacturing capabilities shared by each other.DENSO will continue to maximize its resources in the fields of electrification and clean energy, such as hydrogen, which are expected to see increased adoption, aiming for sustainable growth of these businesses.Going forward, DENSO will continue to steadily advance these initiatives through thoughtful and ongoing dialogue with stakeholders, including customers, business partners and employees. By leveraging the broad technological platform cultivated over many years, DENSO will play a key role in providing diverse solutions across the auto industry, responding to market needs around the world, and contributing to the realization of a sustainable, carbon-neutral society.The transfer will take place only after official approval has been obtained from competition law authorities in all countries and regions concerned, and after fulfilling all other requirements.Overview of the Business Transfer1. Target Business: Spark Plug and Exhaust Gas Sensor business (Oxygen Sensor and Air-Fuel Ratio Sensor)2. Signing Date of the Agreement: September 1, 20253. Transfer Execution Date: To be determined, pending completion of approvals from competition law authorities in all countries and regions concerned, and after fulfilling all other requirements Copyright 2025 JCN Newswire via SeaPRwire.com.

TOKYO, Japan, September 1, 2025 - (JCN Newswire via SeaPRwire.com) – Honda Motor Co., Ltd. (Honda), an official global partner of the World Athletics Championships Tokyo 25 (WCH Tokyo 25), today revealed the list of Honda vehicles to be used as the official vehicles for WCH Tokyo 25, to be held September 13 through 21, 2025.With its theme for WCH Tokyo 25 — “Maximizing the excitement and inspiration from the athletes’ great performance, through the realization of an environmentally-responsible and safe event by providing a wide variety of mobility products equipped with innovative technologies”— Honda will provide a diverse lineup of approximately 120 vehicles, mostly environmentally-responsible vehicles, including fuel cell electric vehicles (FCEVs), battery electric vehicles (BEV) and hybrid electric vehicles (HEVs). All Honda vehicles to be provided as official vehicles will feature a special wrap designed exclusively for the WHC Tokyo 25. Intended useModelCompetition operationMen’s and Women’s MarathonChief Judge’s vehicleCR-V e:FCEVOfficial timing vehicleN-VAN e:Course check vehicleAll-new PreludeCourse check vehicleN-ONE e:Camera bikesCUV e:Supplying electricity to antenna mats for measurement split timesPower Exporter e: 6000 / 9000Throwing eventsRadio-controlled car for retrieval and transportation of throwing implements1/4 model of Honda 0 SUV PrototypeOverall event operationTransportation vehiclesCR-V e:FCEVStep WGN e:HEV modelOdyssey e:HEV modelZR-V e:HEV modelPersonal mobility devicesUNI-ONEStriemo (product of Striemo, Inc.*1)*1 A company originated from the Honda new business creation program, IGNITION.To support men’s and women’s marathon races, the CR-V e:FCEV fuel cell vehicle will serve as the Chief Judge’s vehicle, and N-VAN e: commercial-use mini-EV equipped with Seiko timing equipment will serve as the official timing vehicle. In addition, Honda will provide the Power Exporter e: 6000 and Power Exporter e: 9000 portable external power output devices, which will take electricity from the N-VAN e: and supply electricity to mat antennas stationed at each 5km point on the course to measure the 5km splits of each runner. Men’s/Women’s Marathon Chief Judge’s vehicle(Honda CR-V e:FCEV)Men’s/Women’s Marathon official timing vehicle(Honda N-VAN e:)The all-new Prelude specialty sport model and all-new N-ONE e: mini-EV will be used as course check vehicle to ensure a safe environment before each race. Both vehicles are all-new models scheduled to go on sale in fall 2025. Moreover, the CUV e: electric personal commuter model capable of two-up riding powered by the Honda Mobile Power Pack e: swappable battery will be used as camera bikes to capture the performances of the runners.For the transportation of WCH Tokyo 25 personnel and participants, Honda will provide the CR-V e:FCEV fuel cell electric vehicle, as well as hybrid-electric models, including Step WGN e:HEV, Odyssey e:HEV and ZR-V e:HEV.Furthermore, to enhance mobility and help reduce the workload of WCH Tokyo 25 staff and other stakeholders supporting operation of the WCH Tokyo 25, will utilize Honda UNI-ONE, a hands-free seated personal mobility device the user can steer simply by shifting body weight while sitting.Vehicle exhibit inside the stadium and radio-controlled car for event operations supportDuring the WCH Tokyo 25, for the first time in the history of the World Athletics Championships, a vehicle exhibit will be placed inside the stadium. The vehicle to be on display at the Japan National Stadium is the Honda 0 SUV Prototype. The production model based on this prototype model is scheduled to go on sale first in North America in 2026, followed by global sales. In addition, Honda produced a 1/4 scale radio-controlled model of the Honda 0 SUV Prototype exclusively for the WCH Tokyo 25. This RC car will be used in the throwing events — javelin, hammer, and discus — to retrieve throwing implements and transport them quickly and safely, thereby reducing the workload of staff and contributing to the smooth operation of the throwing events. Image of in-stadium exhibit of Honda 0 SUV Prototype1/4 scale radio-controlled model of Honda 0 SUV PrototypeHonda mobility products exhibit outside the stadium Honda mobility products which will support the WCH Tokyo 25 will be exhibited in an area in front of the Tokyo Metropolitan Gymnasium, adjacent to the National Stadium. The exhibit will feature immersive backgrounds and other effects to create the impression as if the vehicles are in motion, which will offer a unique photo spot for visitors. Moreover, visitors will be able to take photos on the CUV e:, the police motorcycle version of Honda NT1100, and the UNI-ONE. These exhibits are designed to offer experiences through which visitors can feel more connected to the WCH Tokyo 25.PreludeUNI-ONE (with special WCH Tokyo 25 wrap)Honda vehicles and devices on displayAutomobiles:All-new Prelude,N-VAN e: (with special WCH Tokyo 25 wrap)Motorcycles:CUV e: (with special WCH Tokyo 25 wrap)NT1100 (police motorcycle version)Next-generation mobility:UNI-ONE (with special WCH Tokyo 25 wrap)Radio-controlled car:1/4 scale radio-controlled model of Honda 0 SUV Prototype to be used for retrieval of throwing implements: About WCH Tokyo 25Event Name: World Athletics Championships Tokyo 25Organizer/Host: Organizer: World AthleticsHost: Japan Association of Athletics Federations (JAAF)Event Period: September 13 – 21, 2025 (9 days)Number of Participating Countries and Territories: Approximately 200Number of Participating Athletes: Approximately over 2,000Event Venue: Japan National Stadium and other facilities in Tokyo, JapanHonda special World Athletics website Honda will continuously share its stories and passion for supporting athletes who take on challenges in the WCH Tokyo 25 and introduce a wide variety of Honda vehicles serving active roles during the event.URL:https://global.honda/jp/WorldAthletics/ (Japanese)https://global.honda/en/WorldAthletics/ (English)Based on the Honda vision for its sports activities – “To increase the number of people who take on challenges through sports activities and make the lives of all people more enjoyable” – Honda will continue to support various athletes who take on challenges toward the realization of their own dreams. Copyright 2025 JCN Newswire via SeaPRwire.com.

TOKYO and CAMBRIDGE, MA, August 30, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and Biogen Inc. (Nasdaq: BIIB, Headquarters: Cambridge, Massachusetts, CEO: Christopher A. Viehbacher, “Biogen”) announced today that the U.S. Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once weekly lecanemab-irmb subcutaneous injection (U.S. brand name: LEQEMBI® IQLIKTM, pronounced “I Click”) for maintenance dosing. LEQEMBI IQLIK is a subcutaneous autoinjector (SC-AI) developed by Eisai, containing 360 mg/1.8 mL (200 mg/mL) that can be administered in approximately 15 seconds. LEQEMBI IQLIK autoinjector is indicated for maintenance dosing to treat Alzheimer's disease (AD) in patients with mild cognitive impairment (MCI) or mild dementia stage of disease(collectively referred to as early AD) in the U.S. After 18 months of LEQEMBI (lecanemab-irmb) intravenous(IV) treatment at 10 mg/kg every two weeks, patients may either continue IV infusions at 10 mg/kg once every four weeks or start the new weekly 360 mg subcutaneous injection using the LEQEMBI IQLIK autoinjector.Clinical Trials Supporting Subcutaneous Maintenance Dosing ApprovalThe BLA is based on LEQEMBI subcutaneous (SC) sub-studies of the Phase 3 Clarity AD open-label extension (OLE) trial in individuals with early AD, which evaluated a range of subcutaneous doses. Data shows that transitioning to the weekly LEQEMBI IQLIK autoinjector after 18 months of the initiation dose (10 mg/kg IV every two weeks) maintains clinical and biomarker benefits comparable to continued IV dosing.The safety of LEQEMBI IQLIK autoinjector was studied in over 600 patients at a range of doses as part of the Clarity AD OLE.49 patients received a weekly 360 mg subcutaneous maintenance dose after at least 18 months of 10mg/kg IV every two weeks. Importantly, none of these patients experienced any local or systemic injection-related adverse events (AEs).Across all subcutaneous doses, the safety profile was similar to that of the IV maintenance treatment with one key difference: systemic reactions were much less common with subcutaneous dosing—less than 1% compared to approximately 26% with IV infusions. Approximately 11% of patients experienced mild-to-moderate local reactions (such as redness, swelling or itching at the injection site), which did not interfere with continued administration, and less than 1% had mild systemic symptoms such as headache, fever or fatigue.ARIA rates in patients who received a weekly 360 mg subcutaneous maintenance dose were similar to ARIA rates reported in patients who continued with the IV dose after 18 months and are similar to the background rates of ARIA in patients without treatment. ARIA is usually asymptomatic, although serious and life-threatening events can occur. ARIA can be fatal. Most ARIA with LEQEMBI occurs within the first 6 months of IV initiation treatment. Importance of Ongoing TreatmentAD is a progressive, relentless disease with amyloid beta (Aβ) and tau as hallmarks, caused by a continuous underlying neurotoxic process that begins before amyloid plaque removal and continues afterward(1,2,3). Only LEQEMBI fights AD in two ways – targeting both amyloid plaque and protofibrils*, which can impact tau downstream. Due to the reaccumulation of AD biomarkers and return to placebo rate of decline after therapy is stopped(4,5), maintenance treatment with once-weekly SC injection or once every four weeks of IV therapy offers patients options to continue slowing the disease progression and prolong the benefit of therapy, with the goal of helping patients maintain who they are for longer.In the Clarity AD core study, the mean change from baseline between the lecanemab IV once every 2 weeks treated group and the placebo group after 18 months was -0.45 (P=0.00005) on the primary endpoint of CDR-SB global cognitive and functional scale.To provide context, a change from 0.5 to 1 on the Clinical Dementia Rating (CDR) score domains of Memory, Community Affairs and Home/Hobbies reflects a shift from mild impairment to loss of independence. This can affect a person's ability to be left alone safely, recall recent events, participate in daily activities, manage household tasks, and engage in hobbies and intellectual interests(6,7).** At 48 months of treatment through the Clarity AD core study and its OLE, data showed lecanemab demonstrated a reduction in cognitive decline measured by CDR-SB of -1.75 points compared to the expected decline observed in the Alzheimer's Disease Neuroimaging Initiative (ADNI)*2 cohort.Similarly, when benchmarked against the expected decline in the BioFINDER*3 cohort, lecanemab showed a reduction of -2.17 points measured by CDR-SB at the four-year mark.Importance of SC Maintenance OptionTo confirm the safe and effective use of LEQEMBI IQLIK in the expected use environments, additional studies were conducted, including a human factors (HF) study*4 and a tolerability assessment of the device. From the perspective of patients and care partners, benefits included the ability to use the device at home, shortening treatment time and to continue treatment without having to worry about visiting an infusion center. Healthcare providers reported that the device has the potential to provide a new option for patients who are responding well to LEQEMBI and should continue treatment. The SC formulation also has the potential to reduce healthcare resources associated with IV maintenance dosing, such as preparation for infusion and nurse monitoring, while increasing infusion capacity for new eligible patients to begin initiation treatment and streamlining the overall AD treatment pathway.Patient Support ProgramsEisai is committed to ensuring that appropriate patients have access to LEQEMBI. In the U.S. Eisai offersseveral support programs to help patients and care partners. Dedicated Patient Navigators will work directlywith patients and families to navigate treatment and coverage for eligible and appropriate patients and to helpwith what to expect regarding insurance coverage, co-pay and patient access programs. Injection support willalso be available for LEQEMBI IQLIK patients. To learn more visit LEQEMBI.com, call 1-833-4-LEQEMBI (1-833-453-7362), Monday-Friday, 8 a.m. to 8 p.m. Eastern Time.In addition, to support access to LEQEMBI for certain patients who need help paying for their medicines, Eisai’s Patient Assistance Program (PAP) will provide LEQEMBI and LEQEMBI IQLIK at no cost, for eligible uninsured and underinsured patients, including Medicare beneficiaries, who meet financial need and other program criteria.LEQEMBI IQLIK will be launched on October 6, 2025 in the U.S. Click here to learn about how LEQEMBIIQLIK offers patient-centric early Alzheimer's care and our U.S. Pricing Approach.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority. For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202559pdf.pdf Copyright 2025 JCN Newswire via SeaPRwire.com.

TOKYO, Japan, August 29, 2025 - (JCN Newswire via SeaPRwire.com) – Honda Motor Co., Ltd. (Honda) today announced new plans regarding the relocation of its global head office function:1) Honda will relocate its global head office function, before the end of 2029*, to the high-rise office floors of a new mixed-use building currently under construction near Tokyo Station, as a part of the Yaesu 2-Chome Central District Category-I Urban Redevelopment Project (“Yaesu District Redevelopment Area”).2) Honda will conduct a partial transfer of the ownership of Honda Aoyama Building (“Aoyama Bldg.”), the company’s existing head office building in Aoyama, Minato-ku, Tokyo, to Mitsui Fudosan Residential Co., Ltd.Yaesu 2-Chome Central District Category-I Urban Redevelopment ProjectPerspective drawing of exterior (Tokyo Station Yaesu Exit side)It has been 40 years since Honda built the Aoyama Bldg. as its global head office. Amid the continued rapid transformation of society and industry, Honda continues striving to be a “company society wants to exist” into the future. To fulfill this vision, Honda has been carefully considering various approaches to establish a global head office function that will serve as a “hub for transformation and communication that fosters innovation.” In September 2023, Honda decided to proceed with the plan to reconstruct Aoyama Bldg. into a new building, which will enable Honda to realize this vision, with target completion in the fiscal year ending March 31, 2031.The fountainhead of Honda innovations has been the “Waigaya (Y-gaya)” process, a unique communication culture of Honda, in which individual associates transcend their respective roles and positions, and engage in vigorous exchanges of their opinions that yields higher results. Since the temporary relocation of the head office function to Toranomon in Tokyo in May, Honda has been adopting a “one-floor” style of office layout, with associates working in one space on one floor, instead of spread across multiple floors. It has become evident that this office layout has strengthened connections among associates and facilitated more diverse members to come together and engage in more dynamic Waigaya discussions, which has begun generating ideas for a wide range of future innovations. In light of these factors, Honda reconsidered the optimal office conditions for its new global head office, and came to the conclusion that it is the best to relocate its head office to the Yaesu District Redevelopment Area, which includes the former site of the Honda Yaesu Building where the Honda global head office was located from 1960 to 1974. When relocated to the Yaesu District Redevelopment Area, the size of each office floor will be approximately 6.8 times larger than that of the Aoyama Bldg. and approximately 1.8 times larger compared to the current office in Toranomon, whereby Honda will strive to achieve significant enhancement in productivity and new value creation.For Honda, Yaesu is a place of special significance, as it was the location of the first operation base where the company strived to establish a presence in Tokyo, began taking on challenges to become a global brand, and laid the foundation for what Honda has become today. Moreover, the Yaesu District has been considered one of the world’s most renowned business districts, serving as a hub for cutting-edge technology and information, with its proximity to Tokyo Station providing excellent access both domestically and internationally. Currently, redevelopment projects are underway across the district, and further enhancement of urban city functions and services is expected in the future.Regarding the Aoyama Bldg., after thorough consideration of the traditional Honda approach to building design as well as the current business environment surrounding Honda, the company decided to transfer a portion of its ownership of the building and land of Aoyama Bldg. to Mitsui Fudosan Residential. The site of Aoyama Bldg. served as the second global head office building owned by Honda in Tokyo for approximately 40 years since 1985, and also housed Honda Welcome Plaza Aoyama to invite the public to see and experience Honda products and technologies, and it will remain a place of deep significance for Honda. Following the partial transfer, Honda and Mitsui Fudosan Residential will jointly construct a new building on the site of Aoyama Bldg. Once completed, Honda is planning to make use of part of the new building, and will explore a range of ideas and opportunities to make it a venue to further enhance Honda brand value.Honda global head office relocation schedule- May 2025 — Honda head office functions relocated temporarily to offices in Toranomon Alcea Tower and Honda Wako Building. - Before the end of 2029* — Honda head office functions will be relocated permanently on high-rise office floors of the new building in Yaesu District Redevelopment AreaOverview of Yaesu 2-Chome Central District Category-I Urban Redevelopment ProjectProject nameYaesu 2-Chome Central District Category-I Urban Redevelopment ProjectBuilderYaesu 2-Chome Central District Urban Redevelopment Project AssociationLocation4, 5, 6 and 7, Yaesu 2-Chome, Chuo-ku, Tokyo, JapanCompletionJanuary 31, 2029 (planned)Number of floors/ max height43 floors above ground, 3 floors below ground, approx. 744 ft. (approx. 227 m)Site areaApprox. 210,542 ft2(approx. 19,560 m2)Total floor areaApprox. 4,190,282 ft2(approx. 389,290 m2)Main purposesOffices, retail facilities, theater, serviced apartments, international school, bus terminal, parking lot, etc.ReferenceMitsui Fudosan Group news release:Yaesu 2-Chome Central District Category-I Urban Redevelopment Project:Partial Transfer of Rights to Honda and Joint Reconstruction of Honda Aoyama BuildingURL: https://www.mitsuifudosan.co.jp/english/corporate/news/2025/0829_01/* Planned completion schedule as of August 2025. The schedule is subject to change in the future. Copyright 2025 JCN Newswire via SeaPRwire.com.

TOKYO, August 29, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) announced today that it has received orphan drug designation for anticancer agent the EZH2*1 inhibitor tazemetostat hydrobromide (generic name, product name “Tazverik® Tablets 200 mg”, “tazemetostat”) for unresectable INI1*2-negative epithelioid sarcoma that has progressed after chemotherapy, from the Ministry of Health, Labour and Welfare (MHLW).Epithelioid sarcoma is a type of soft tissue sarcoma that is a rare cancer estimated to account for about 1% of all soft tissue sarcoma.1 Only 174 cases were registered from major hospitals across Japan over a10-year period from 2006 to 2015.2 Loss of INI1, which is a negative regulator of EZH2, is observed in over 90% of epithelioid sarcoma cases,3 leading to EZH2 activation that is believed to drive tumor onset and malignant progression. Treatment options are limited, resulting in an extremely high unmet medical need.Tazemetostat was approved in Japan in June 2021 for relapsed or refractory EZH2 gene mutation-positive follicular lymphoma (only when standard treatment is not applicable). For INI1-negative unresectable epithelioid sarcoma that has progressed after chemotherapy, a Phase II investigator-initiated trial of tazemetostat (A Phase II Trial of Tazemetostat for Patients with Unresectable or Metastatic Epithelioid Sarcoma: TAZETTA trial), led by the National Cancer Center Hospital, is currently underway.Eisai identifies oncology as one of its priority areas and strives to develop ground breaking new therapies aimed at curing cancer. We remain committed to meeting the diverse needs of cancer patients worldwide, their families, and healthcare professionals, and to enhancing the benefits delivered to them.*1 A type of histone methyl group elongation enzyme, it is a protein that controls gene expression by methylating the 27th lysine residue of histone H3 (H3K27).*2 One of the proteins that make up the SWI/SNF chromatin complex (a protein complex that modifies chromatinstructure to regulate gene function), it is involved in regulating gene expression.For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202558pdf.pdfMedia Inquiries:Public Relations Department,Eisai Co., Ltd.+81-(0)3-3817-5120 Copyright 2025 JCN Newswire via SeaPRwire.com.

Completion of strategic acquisition affirms Hitachi Energy’s position as a market and technology leader in advancing energy storage innovation - a cornerstone of secure energy transitionsPower electronics with advanced digital capabilities are critical to ensure reliability and stability of the electric gridZurich, Switzerland, August 28, 2025 - (JCN Newswire via SeaPRwire.com) - Hitachi Energy, a global leader in electrification, has completed the acquisition of the remaining stake in eks Energy, a technology and market leader in power electronics and control solutions to deliver a scalable, flexible, and complete approach for energy storage customers. Hitachi Energy acquired a majority stake in eks Energy in 2023. As energy storage emerges as a cornerstone of grid stability, reliability and energy security, the IEA1 has called for a sixfold increase in global storage capacity to 1,500 GW by 2030. Underscoring this urgency, the COP29 Global Pledge2 highlights energy storage and grid infrastructure as essential to building resilient, decarbonized energy systems worldwide.The integration of eks Energy’s innovative technology, talent and enterprising spirit provides Hitachi Energy with greater strategic and operational flexibility. It allows the company to streamline solution integration, further expand its power conversion and energy storage business, and respond rapidly to evolving customer needs.“As the worldwide market leader in grid automation solutions, the acquisition of eks Energy strengthens our leadership position, enabling one of the industry’s most comprehensive solution portfolios that combines proven converter and control technology with Hitachi Energy’s global scale, unparalleled grid expertise, and digital capabilities,” said Massimo Danieli, Managing Director of Hitachi Energy’s Business Unit Grid Automation. “The acquisition furthers our global strategy ensuring continuity for existing customers while unlocking new opportunities for innovation and growth.”Since 2023, the team has strengthened capabilities for power conversion solutions, including the development of a center of excellence in Seville, Spain, where the business is headquartered, to foster deeper collaboration across R&D, product development, and customer delivery. Additionally, Hitachi Energy’s power conversion solutions business has demonstrated strong commercial momentum and technical leadership across the globe, playing a key role in major energy storage projects such as the Waratah Super Battery in New South Wales, which recently reached key milestones including commercial operation (COD) and full registration under the System Integrity Protection Scheme (SIPS), a fast-acting grid support system designed to maintain stability during critical events. The business has also expanded its global footprint, positioning Hitachi Energy to better serve energy storage customers across key global markets. The successful development and launch earlier this year of a new liquid-cooled WD4 converter platform further enhances performance and scalability across BESS applications for system integrators.Power converters play a critical role connecting power source with power supply, making sure that currents and voltage are balanced correctly for end user demand. They are data-intensive systems, and when paired with Hitachi Energy’s internet of things (IoT) connectivity and energy management capabilities, deliver rich insights and analytics to maximize reliable energy supply. The completion of the acquisition will enable Hitachi Energy to innovate faster and improve the technology at this critical grid connection point.Hitachi Energy is making unparalleled investments in its global footprint and people, continuously pioneering technologies to enable the world’s energy system to be more sustainable, secure, resilient and acquisitions are playing a critical role in supporting the company’s broader strategy. 1 Outlook for battery demand and supply – Batteries and Secure Energy Transitions – Analysis - IEA2 COP29 Global Energy Storage and Grids PledgeAbout Hitachi EnergyHitachi Energy is a global technology leader in electrification, powering a sustainable energy future with innovative power grid technologies with digital at the core. Over three billion people depend on our technologies to power their daily lives. With over a century in pioneering mission-critical technologies like high-voltage, transformers, automation, and power electronics, we are addressing the most urgent energy challenge of our time – balancing soaring electricity demand, while decarbonizing the power system. With an unparalleled installed base in over 140 countries, we co-create and build long-term partnerships across the utility, industry, transportation, data centers, and infrastructure sectors. Headquartered in Switzerland, we employ over 50,000 people in 60 countries and generate revenues of around $16 billion USD.Https://www.hitachienergy.comhttps://www.linkedin.com/company/hitachienergyhttps://x.com/HitachiEnergyAbout Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT (Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are inbalance. Hitachi operates globally in four sectors – Digital Systems & Hitachi Energy is a global technology leader in electrification, powering a sustainable energy future with innovative power grid technologies with digital at the core. Over three billion people depend on our technologies to power their daily lives. Services, Energy, Mobility, and Connective Industries – and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024 (ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at www.hitachi.com. Copyright 2025 JCN Newswire via SeaPRwire.com.

Massachusetts, USA, September 2, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Corporation ("MC”) is pleased to announce its participation in a third-party allotment of shares by Commonwealth Fusion Systems LLC (Headquarter: Massachusetts, USA, Representative: Bob Mumgaard, “CFS”), a fusion energy start-up originating from MIT *1. This investment was made in collaboration with a consortium of 12 Japanese companies *2 (“Japanese Consortium”). In the field of fusion energy, this investment builds on MC’s previous investment in Kyoto Fusioneering Ltd., announced on May 17, 2023.*1 Massachusetts Institute of Technology*2 MC, Mitsui & Co., Ltd., Kansai Electric Power Co., Inc., JERA, Mitsui O.S.K. Lines, Ltd., JGC, Development Bank of Japan, Inc., NTT Corporation, Fujikura Corporation, Sumitomo Mitsui Banking Corporation, Sumitomo Mitsui Trust Bank, Limited, Mitsui Fudosan Co., Ltd.Fusion energy is produced when two light nuclei, typically deuterium and tritium, collide to form a single heavier nucleus, helium. This is the same process that powers the Sun and other stars. Since no carbon dioxide is emitted during power generation and the fuel is abundantly available in seawater, fusion offers an almost inexhaustible energy source. A small amount of fuel can produce a tremendous amount of energy. Fusion is gaining global attention as a next-generation energy source that supports decarbonization and ensures a stable energy supply. In June 2025, the Japanese government revised its “Fusion Energy Innovation Strategy,” which outlines the development and promotion of fusion energy. This policy aims to position Japan as a global leader in power generation by the 2030s.CFS, a spin-off company of MIT, is the world’s leading and largest private fusion company, utilizing the magnetic confinement system (tokamak type) *3. The company plans to build the world's first commercial fusion power plant "ARC" in Virginia in the United States, with the intent of generating electricity in the early 2030s. In June of this year, CFS announced that it signed a power purchase agreement with Google for 200 megawatts of electricity from its first ARC power plant.The Japanese Consortium will acquire technical and commercial expertise in policy, regulatory, and the development, construction, operation, and maintenance of ARC from CFS's commercialization projects in the United States. In addition, each consortium company will bring together its know-how and expertise and aspire to expedite the commercialization and industrialization of fusion energy power generation in Japan.The collaboration between the Japanese Consortium and CFS is consistent with the Japan – U.S. joint partnership to accelerate the development and commercialization of fusion energy power generation in Japan and the United States, and represents a strong commitment and growing momentum toward the early realization of commercialization in both countries.*3 A torus-shaped fusion energy device that uses a strong magnetic field to confine ultra-high temperature plasmaThrough this investment, MC seeks to acquire cutting-edge knowledge in fusion energy and contribute to both decarbonization and a stable energy supply by leveraging its extensive networks and industrial capabilities to support the practical application of fusion technologies.MaterialityBased on the Three Corporate Principles, which serve as MC’s core philosophy, MC has continued to grow together with society by contributing to the sustainable development of society through its business activities while pursuing value creation. While continuously creating Shared Value guided by the Materiality, a set of crucial societal issues, MC will continue to strengthen its efforts towards sustainable corporate growth. Guided by this Materiality, MC will continue to strengthen its efforts towards sustainable corporate growth. Out of the six material issues relating to “Realizing a Carbon Neutral Society and Striving to Enrich Society Both Materially and Spiritually”, this project’s activities particularly support "Contributing to Decarbonized Societies", “Promoting Stable, Sustainable Societies and Lifestyles” and “Utilizing Innovation to Address Societal Needs”.Inquiry RecipientMitsubishi CorporationTelephone:+81-3-3210-2171 Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, September 2, 2025 - (JCN Newswire via SeaPRwire.com) - Hitachi, Ltd. (TSE:6501, "Hitachi") has been certified as a Gold Partner*1 of Scaled Agile, Inc. ("SAI"), the provider of SAFe®, the world's most trusted system for business agility.SAFe is a management framework that supports organizational transformation and business agility, helping to enhance competitiveness and maximize customer value and is widely adopted globally. Within the Hitachi Group, GlobalLogic was certified as a Silver Partner of SAI in 2021 and has been supporting agile DX transformation based on customer experience.Amid increasingly rapid social change and growing uncertainty, Hitachi will apply SAFe as a common framework across One Hitachi to support customers globally in rapidly adapting to change and continuously creating value. For example, by applying SAFe to the implementation of "HMAX*2", which embodies Lumada 3.0 and aims to solve customer and societal challenges by converting data into value using Hitachi's domain knowledge and AI, Hitachi seeks to accelerate the value delivery cycle.Going forward, through this certification and as part of SAI's official partner network, Hitachi will utilize SAFe as a methodology for enterprise-level agile development. Hitachi will flexibly and continuously support system development management that is aligned with customers' business strategies in response to changes in society and the market environment. Additionally, Hitachi will establish a framework for implementing SAFe within the company and systematically advance human resource development to increase the number of employees with SAFe expertise to 5,000, thereby strengthening practical capabilities and agility.Through these efforts, Hitachi will accelerate social innovation and contribute to the realization of a "Harmonized Society" where environment, wellbeing, and economic growth coexist in harmony.*1 Certification awarded to organizations with five or more certified SAFe consultants (SPCs) who are recognized as capable of leading agile transformations for customers at the enterprise level.*2 September 24, 2024: Hitachi Rail Unveils the ‘HMAX’ AI Solution, Accelerated by NVIDIA, to Optimize Trains, Signaling and Infrastructurehttps://www.hitachi.com/New/cnews/month/2024/09/240924c.htmlBackgroundIn recent years, agile methodologies have become increasingly widespread in system development as companies seek to respond flexibly to uncertain and rapidly changing market environments and strengthen their competitiveness. Hitachi launched its "Agile Development Consulting Service" in 2019 with the aim of providing efficient system development and high-quality IT services. In addition, Hitachi has responded to numerous agile development projects to quickly address changes in our customers' business strategies and market needs, contributing to the enhancement of their experience value. Furthermore, Hitachi has actively worked to improve the speed, flexibility, and scalability of system development by adapting the agile development methodologies used at GlobalLogic for the Japanese market, and applying them to enterprise systems that support the core of business operations. Today, rapid development and service delivery aligned with changes in society and market conditions require organizations to undergo transformation in sync with their corporate strategies.As a result, there is a growing need to leverage proven management frameworks that enhance business agility by flexibly translating those requirements into system development.Future Initiatives1. Strengthening System Development Management Aligned with Customer Business Strategies.Hitachi will leverage SAFe through this partner certification to further accelerate Social Innovation Business by leveraging its strengths in IT, OT, and products. Specifically, we will adopt SAFe, a management framework aligned with business strategy, as a standard methodology for enterprise-level agile system development to enhance business agility. This will enable us to respond flexibly and swiftly to future changes in the business environment, thereby contributing to our customers' sustainable growth and accelerated digital transformation.2. Advancing Human Resource Development.In addition to its framework, SAFe provides certified training courses and agile development coaching for members. Hitachi will utilize these resources to further focus on developing agile human resources, increasing the number of employees with SAFe knowledge to 5,000. Additionally, through Gold Partner certification, Hitachi will gain direct access to the latest insights and training programs from SAI, as well as global best practices from the SAFe partner network worldwide, and will actively utilize these resources.Through these initiatives, Hitachi will systematically establish a framework for SAFe implementation and human resource development within the company, thereby strengthening its practical capabilities and agility from a human resource perspective.Hitachi will continue to promote Social Innovation Business that leverage agile development methods and digital technologies to solve the challenges faced by our customers and society. We will also maximize the knowledge and global network we have cultivated as a SAFe partner to accelerate our customers' DX and contribute to the enhancement of their corporate value.Comments from Phil Knight - VP, Partner Alliances, Scaled Agile, Inc."We are delighted to welcome Hitachi, Ltd. as a Gold Partner in the Scaled Agile Partner Network. By leveraging SAFe® to drive enterprise-wide agile transformation and applying it to their platforms and solutions, Hitachi will further maximize customer value creation. Through this partnership, we look forward to accelerating the adoption of business agility across Japan more than ever before."About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT(Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries –and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024(ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at www.hitachi.com.Business ContactProject Management DivisionDigital Systems & Services Business ManagementDivisionDigital Systems & Services Business DivisionHitachi, Ltdspc-info@ml.itg.hitachi.co.jp Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

KARIYA, JAPAN, September 1, 2025 - (JCN Newswire via SeaPRwire.com) - DENSO CORPORATION (hereinafter “DENSO”) today announced that its Board of Directors has resolved to transfer its Spark Plug and Exhaust Gas Sensor business (Oxygen Sensor and Air-Fuel Ratio Sensor), to Niterra Co., Ltd (hereinafter “Niterra”). The two parties reached a decision to sign the business transfer agreement during a board of directors meeting on September 1st, 2025.In the process of achieving a carbon neutral society, electrified vehicles are expected to become more widespread throughout the auto industry. At the same time, powertrain diversification is expected to continue progressing, in response to differing energy and fuel needs across regions and countries. In such market environment changes, DENSO recognizes that advancing product innovation across all domains and establishing a sustainable supply framework aligned with the anticipated market scale, are challenges for the entire auto industry.Under all these factors, on July 10, 2023, DENSO completed an MOU* to transfer business operations for select internal combustion engine parts to Niterra, which boasts some of the world’s leading technologies in its field.Since then, through extensive discussions and deliberations, the two parties reached an agreement on the business transfer. This decision was made while sharing a common understanding of a strong commitment to the technology and quality of Spark Plug and Exhaust Gas Sensor. Through this transfer, both companies will enhance the product capabilities of internal combustion engines, by integrating technologies and manufacturing capabilities shared by each other.DENSO will continue to maximize its resources in the fields of electrification and clean energy, such as hydrogen, which are expected to see increased adoption, aiming for sustainable growth of these businesses.Going forward, DENSO will continue to steadily advance these initiatives through thoughtful and ongoing dialogue with stakeholders, including customers, business partners and employees. By leveraging the broad technological platform cultivated over many years, DENSO will play a key role in providing diverse solutions across the auto industry, responding to market needs around the world, and contributing to the realization of a sustainable, carbon-neutral society.The transfer will take place only after official approval has been obtained from competition law authorities in all countries and regions concerned, and after fulfilling all other requirements.Overview of the Business Transfer1. Target Business: Spark Plug and Exhaust Gas Sensor business (Oxygen Sensor and Air-Fuel Ratio Sensor)2. Signing Date of the Agreement: September 1, 20253. Transfer Execution Date: To be determined, pending completion of approvals from competition law authorities in all countries and regions concerned, and after fulfilling all other requirements Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, September 1, 2025 - (JCN Newswire via SeaPRwire.com) – Honda Motor Co., Ltd. (Honda), an official global partner of the World Athletics Championships Tokyo 25 (WCH Tokyo 25), today revealed the list of Honda vehicles to be used as the official vehicles for WCH Tokyo 25, to be held September 13 through 21, 2025.With its theme for WCH Tokyo 25 — “Maximizing the excitement and inspiration from the athletes’ great performance, through the realization of an environmentally-responsible and safe event by providing a wide variety of mobility products equipped with innovative technologies”— Honda will provide a diverse lineup of approximately 120 vehicles, mostly environmentally-responsible vehicles, including fuel cell electric vehicles (FCEVs), battery electric vehicles (BEV) and hybrid electric vehicles (HEVs). All Honda vehicles to be provided as official vehicles will feature a special wrap designed exclusively for the WHC Tokyo 25. Intended useModelCompetition operationMen’s and Women’s MarathonChief Judge’s vehicleCR-V e:FCEVOfficial timing vehicleN-VAN e:Course check vehicleAll-new PreludeCourse check vehicleN-ONE e:Camera bikesCUV e:Supplying electricity to antenna mats for measurement split timesPower Exporter e: 6000 / 9000Throwing eventsRadio-controlled car for retrieval and transportation of throwing implements1/4 model of Honda 0 SUV PrototypeOverall event operationTransportation vehiclesCR-V e:FCEVStep WGN e:HEV modelOdyssey e:HEV modelZR-V e:HEV modelPersonal mobility devicesUNI-ONEStriemo (product of Striemo, Inc.*1)*1 A company originated from the Honda new business creation program, IGNITION.To support men’s and women’s marathon races, the CR-V e:FCEV fuel cell vehicle will serve as the Chief Judge’s vehicle, and N-VAN e: commercial-use mini-EV equipped with Seiko timing equipment will serve as the official timing vehicle. In addition, Honda will provide the Power Exporter e: 6000 and Power Exporter e: 9000 portable external power output devices, which will take electricity from the N-VAN e: and supply electricity to mat antennas stationed at each 5km point on the course to measure the 5km splits of each runner. Men’s/Women’s Marathon Chief Judge’s vehicle(Honda CR-V e:FCEV)Men’s/Women’s Marathon official timing vehicle(Honda N-VAN e:)The all-new Prelude specialty sport model and all-new N-ONE e: mini-EV will be used as course check vehicle to ensure a safe environment before each race. Both vehicles are all-new models scheduled to go on sale in fall 2025. Moreover, the CUV e: electric personal commuter model capable of two-up riding powered by the Honda Mobile Power Pack e: swappable battery will be used as camera bikes to capture the performances of the runners.For the transportation of WCH Tokyo 25 personnel and participants, Honda will provide the CR-V e:FCEV fuel cell electric vehicle, as well as hybrid-electric models, including Step WGN e:HEV, Odyssey e:HEV and ZR-V e:HEV.Furthermore, to enhance mobility and help reduce the workload of WCH Tokyo 25 staff and other stakeholders supporting operation of the WCH Tokyo 25, will utilize Honda UNI-ONE, a hands-free seated personal mobility device the user can steer simply by shifting body weight while sitting.Vehicle exhibit inside the stadium and radio-controlled car for event operations supportDuring the WCH Tokyo 25, for the first time in the history of the World Athletics Championships, a vehicle exhibit will be placed inside the stadium. The vehicle to be on display at the Japan National Stadium is the Honda 0 SUV Prototype. The production model based on this prototype model is scheduled to go on sale first in North America in 2026, followed by global sales. In addition, Honda produced a 1/4 scale radio-controlled model of the Honda 0 SUV Prototype exclusively for the WCH Tokyo 25. This RC car will be used in the throwing events — javelin, hammer, and discus — to retrieve throwing implements and transport them quickly and safely, thereby reducing the workload of staff and contributing to the smooth operation of the throwing events. Image of in-stadium exhibit of Honda 0 SUV Prototype1/4 scale radio-controlled model of Honda 0 SUV PrototypeHonda mobility products exhibit outside the stadium Honda mobility products which will support the WCH Tokyo 25 will be exhibited in an area in front of the Tokyo Metropolitan Gymnasium, adjacent to the National Stadium. The exhibit will feature immersive backgrounds and other effects to create the impression as if the vehicles are in motion, which will offer a unique photo spot for visitors. Moreover, visitors will be able to take photos on the CUV e:, the police motorcycle version of Honda NT1100, and the UNI-ONE. These exhibits are designed to offer experiences through which visitors can feel more connected to the WCH Tokyo 25.PreludeUNI-ONE (with special WCH Tokyo 25 wrap)Honda vehicles and devices on displayAutomobiles:All-new Prelude,N-VAN e: (with special WCH Tokyo 25 wrap)Motorcycles:CUV e: (with special WCH Tokyo 25 wrap)NT1100 (police motorcycle version)Next-generation mobility:UNI-ONE (with special WCH Tokyo 25 wrap)Radio-controlled car:1/4 scale radio-controlled model of Honda 0 SUV Prototype to be used for retrieval of throwing implements: About WCH Tokyo 25Event Name: World Athletics Championships Tokyo 25Organizer/Host: Organizer: World AthleticsHost: Japan Association of Athletics Federations (JAAF)Event Period: September 13 – 21, 2025 (9 days)Number of Participating Countries and Territories: Approximately 200Number of Participating Athletes: Approximately over 2,000Event Venue: Japan National Stadium and other facilities in Tokyo, JapanHonda special World Athletics website Honda will continuously share its stories and passion for supporting athletes who take on challenges in the WCH Tokyo 25 and introduce a wide variety of Honda vehicles serving active roles during the event.URL:https://global.honda/jp/WorldAthletics/ (Japanese)https://global.honda/en/WorldAthletics/ (English)Based on the Honda vision for its sports activities – “To increase the number of people who take on challenges through sports activities and make the lives of all people more enjoyable” – Honda will continue to support various athletes who take on challenges toward the realization of their own dreams. Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO and CAMBRIDGE, MA, August 30, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and Biogen Inc. (Nasdaq: BIIB, Headquarters: Cambridge, Massachusetts, CEO: Christopher A. Viehbacher, “Biogen”) announced today that the U.S. Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for once weekly lecanemab-irmb subcutaneous injection (U.S. brand name: LEQEMBI® IQLIKTM, pronounced “I Click”) for maintenance dosing. LEQEMBI IQLIK is a subcutaneous autoinjector (SC-AI) developed by Eisai, containing 360 mg/1.8 mL (200 mg/mL) that can be administered in approximately 15 seconds. LEQEMBI IQLIK autoinjector is indicated for maintenance dosing to treat Alzheimer's disease (AD) in patients with mild cognitive impairment (MCI) or mild dementia stage of disease(collectively referred to as early AD) in the U.S. After 18 months of LEQEMBI (lecanemab-irmb) intravenous(IV) treatment at 10 mg/kg every two weeks, patients may either continue IV infusions at 10 mg/kg once every four weeks or start the new weekly 360 mg subcutaneous injection using the LEQEMBI IQLIK autoinjector.Clinical Trials Supporting Subcutaneous Maintenance Dosing ApprovalThe BLA is based on LEQEMBI subcutaneous (SC) sub-studies of the Phase 3 Clarity AD open-label extension (OLE) trial in individuals with early AD, which evaluated a range of subcutaneous doses. Data shows that transitioning to the weekly LEQEMBI IQLIK autoinjector after 18 months of the initiation dose (10 mg/kg IV every two weeks) maintains clinical and biomarker benefits comparable to continued IV dosing.The safety of LEQEMBI IQLIK autoinjector was studied in over 600 patients at a range of doses as part of the Clarity AD OLE.49 patients received a weekly 360 mg subcutaneous maintenance dose after at least 18 months of 10mg/kg IV every two weeks. Importantly, none of these patients experienced any local or systemic injection-related adverse events (AEs).Across all subcutaneous doses, the safety profile was similar to that of the IV maintenance treatment with one key difference: systemic reactions were much less common with subcutaneous dosing—less than 1% compared to approximately 26% with IV infusions. Approximately 11% of patients experienced mild-to-moderate local reactions (such as redness, swelling or itching at the injection site), which did not interfere with continued administration, and less than 1% had mild systemic symptoms such as headache, fever or fatigue.ARIA rates in patients who received a weekly 360 mg subcutaneous maintenance dose were similar to ARIA rates reported in patients who continued with the IV dose after 18 months and are similar to the background rates of ARIA in patients without treatment. ARIA is usually asymptomatic, although serious and life-threatening events can occur. ARIA can be fatal. Most ARIA with LEQEMBI occurs within the first 6 months of IV initiation treatment. Importance of Ongoing TreatmentAD is a progressive, relentless disease with amyloid beta (Aβ) and tau as hallmarks, caused by a continuous underlying neurotoxic process that begins before amyloid plaque removal and continues afterward(1,2,3). Only LEQEMBI fights AD in two ways – targeting both amyloid plaque and protofibrils*, which can impact tau downstream. Due to the reaccumulation of AD biomarkers and return to placebo rate of decline after therapy is stopped(4,5), maintenance treatment with once-weekly SC injection or once every four weeks of IV therapy offers patients options to continue slowing the disease progression and prolong the benefit of therapy, with the goal of helping patients maintain who they are for longer.In the Clarity AD core study, the mean change from baseline between the lecanemab IV once every 2 weeks treated group and the placebo group after 18 months was -0.45 (P=0.00005) on the primary endpoint of CDR-SB global cognitive and functional scale.To provide context, a change from 0.5 to 1 on the Clinical Dementia Rating (CDR) score domains of Memory, Community Affairs and Home/Hobbies reflects a shift from mild impairment to loss of independence. This can affect a person's ability to be left alone safely, recall recent events, participate in daily activities, manage household tasks, and engage in hobbies and intellectual interests(6,7).** At 48 months of treatment through the Clarity AD core study and its OLE, data showed lecanemab demonstrated a reduction in cognitive decline measured by CDR-SB of -1.75 points compared to the expected decline observed in the Alzheimer's Disease Neuroimaging Initiative (ADNI)*2 cohort.Similarly, when benchmarked against the expected decline in the BioFINDER*3 cohort, lecanemab showed a reduction of -2.17 points measured by CDR-SB at the four-year mark.Importance of SC Maintenance OptionTo confirm the safe and effective use of LEQEMBI IQLIK in the expected use environments, additional studies were conducted, including a human factors (HF) study*4 and a tolerability assessment of the device. From the perspective of patients and care partners, benefits included the ability to use the device at home, shortening treatment time and to continue treatment without having to worry about visiting an infusion center. Healthcare providers reported that the device has the potential to provide a new option for patients who are responding well to LEQEMBI and should continue treatment. The SC formulation also has the potential to reduce healthcare resources associated with IV maintenance dosing, such as preparation for infusion and nurse monitoring, while increasing infusion capacity for new eligible patients to begin initiation treatment and streamlining the overall AD treatment pathway.Patient Support ProgramsEisai is committed to ensuring that appropriate patients have access to LEQEMBI. In the U.S. Eisai offersseveral support programs to help patients and care partners. Dedicated Patient Navigators will work directlywith patients and families to navigate treatment and coverage for eligible and appropriate patients and to helpwith what to expect regarding insurance coverage, co-pay and patient access programs. Injection support willalso be available for LEQEMBI IQLIK patients. To learn more visit LEQEMBI.com, call 1-833-4-LEQEMBI (1-833-453-7362), Monday-Friday, 8 a.m. to 8 p.m. Eastern Time.In addition, to support access to LEQEMBI for certain patients who need help paying for their medicines, Eisai’s Patient Assistance Program (PAP) will provide LEQEMBI and LEQEMBI IQLIK at no cost, for eligible uninsured and underinsured patients, including Medicare beneficiaries, who meet financial need and other program criteria.LEQEMBI IQLIK will be launched on October 6, 2025 in the U.S. Click here to learn about how LEQEMBIIQLIK offers patient-centric early Alzheimer's care and our U.S. Pricing Approach.Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority. For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202559pdf.pdf Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, August 29, 2025 - (JCN Newswire via SeaPRwire.com) – Honda Motor Co., Ltd. (Honda) today announced new plans regarding the relocation of its global head office function:1) Honda will relocate its global head office function, before the end of 2029*, to the high-rise office floors of a new mixed-use building currently under construction near Tokyo Station, as a part of the Yaesu 2-Chome Central District Category-I Urban Redevelopment Project (“Yaesu District Redevelopment Area”).2) Honda will conduct a partial transfer of the ownership of Honda Aoyama Building (“Aoyama Bldg.”), the company’s existing head office building in Aoyama, Minato-ku, Tokyo, to Mitsui Fudosan Residential Co., Ltd.Yaesu 2-Chome Central District Category-I Urban Redevelopment ProjectPerspective drawing of exterior (Tokyo Station Yaesu Exit side)It has been 40 years since Honda built the Aoyama Bldg. as its global head office. Amid the continued rapid transformation of society and industry, Honda continues striving to be a “company society wants to exist” into the future. To fulfill this vision, Honda has been carefully considering various approaches to establish a global head office function that will serve as a “hub for transformation and communication that fosters innovation.” In September 2023, Honda decided to proceed with the plan to reconstruct Aoyama Bldg. into a new building, which will enable Honda to realize this vision, with target completion in the fiscal year ending March 31, 2031.The fountainhead of Honda innovations has been the “Waigaya (Y-gaya)” process, a unique communication culture of Honda, in which individual associates transcend their respective roles and positions, and engage in vigorous exchanges of their opinions that yields higher results. Since the temporary relocation of the head office function to Toranomon in Tokyo in May, Honda has been adopting a “one-floor” style of office layout, with associates working in one space on one floor, instead of spread across multiple floors. It has become evident that this office layout has strengthened connections among associates and facilitated more diverse members to come together and engage in more dynamic Waigaya discussions, which has begun generating ideas for a wide range of future innovations. In light of these factors, Honda reconsidered the optimal office conditions for its new global head office, and came to the conclusion that it is the best to relocate its head office to the Yaesu District Redevelopment Area, which includes the former site of the Honda Yaesu Building where the Honda global head office was located from 1960 to 1974. When relocated to the Yaesu District Redevelopment Area, the size of each office floor will be approximately 6.8 times larger than that of the Aoyama Bldg. and approximately 1.8 times larger compared to the current office in Toranomon, whereby Honda will strive to achieve significant enhancement in productivity and new value creation.For Honda, Yaesu is a place of special significance, as it was the location of the first operation base where the company strived to establish a presence in Tokyo, began taking on challenges to become a global brand, and laid the foundation for what Honda has become today. Moreover, the Yaesu District has been considered one of the world’s most renowned business districts, serving as a hub for cutting-edge technology and information, with its proximity to Tokyo Station providing excellent access both domestically and internationally. Currently, redevelopment projects are underway across the district, and further enhancement of urban city functions and services is expected in the future.Regarding the Aoyama Bldg., after thorough consideration of the traditional Honda approach to building design as well as the current business environment surrounding Honda, the company decided to transfer a portion of its ownership of the building and land of Aoyama Bldg. to Mitsui Fudosan Residential. The site of Aoyama Bldg. served as the second global head office building owned by Honda in Tokyo for approximately 40 years since 1985, and also housed Honda Welcome Plaza Aoyama to invite the public to see and experience Honda products and technologies, and it will remain a place of deep significance for Honda. Following the partial transfer, Honda and Mitsui Fudosan Residential will jointly construct a new building on the site of Aoyama Bldg. Once completed, Honda is planning to make use of part of the new building, and will explore a range of ideas and opportunities to make it a venue to further enhance Honda brand value.Honda global head office relocation schedule- May 2025 — Honda head office functions relocated temporarily to offices in Toranomon Alcea Tower and Honda Wako Building. - Before the end of 2029* — Honda head office functions will be relocated permanently on high-rise office floors of the new building in Yaesu District Redevelopment AreaOverview of Yaesu 2-Chome Central District Category-I Urban Redevelopment ProjectProject nameYaesu 2-Chome Central District Category-I Urban Redevelopment ProjectBuilderYaesu 2-Chome Central District Urban Redevelopment Project AssociationLocation4, 5, 6 and 7, Yaesu 2-Chome, Chuo-ku, Tokyo, JapanCompletionJanuary 31, 2029 (planned)Number of floors/ max height43 floors above ground, 3 floors below ground, approx. 744 ft. (approx. 227 m)Site areaApprox. 210,542 ft2(approx. 19,560 m2)Total floor areaApprox. 4,190,282 ft2(approx. 389,290 m2)Main purposesOffices, retail facilities, theater, serviced apartments, international school, bus terminal, parking lot, etc.ReferenceMitsui Fudosan Group news release:Yaesu 2-Chome Central District Category-I Urban Redevelopment Project:Partial Transfer of Rights to Honda and Joint Reconstruction of Honda Aoyama BuildingURL: https://www.mitsuifudosan.co.jp/english/corporate/news/2025/0829_01/* Planned completion schedule as of August 2025. The schedule is subject to change in the future. Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, August 29, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) announced today that it has received orphan drug designation for anticancer agent the EZH2*1 inhibitor tazemetostat hydrobromide (generic name, product name “Tazverik® Tablets 200 mg”, “tazemetostat”) for unresectable INI1*2-negative epithelioid sarcoma that has progressed after chemotherapy, from the Ministry of Health, Labour and Welfare (MHLW).Epithelioid sarcoma is a type of soft tissue sarcoma that is a rare cancer estimated to account for about 1% of all soft tissue sarcoma.1 Only 174 cases were registered from major hospitals across Japan over a10-year period from 2006 to 2015.2 Loss of INI1, which is a negative regulator of EZH2, is observed in over 90% of epithelioid sarcoma cases,3 leading to EZH2 activation that is believed to drive tumor onset and malignant progression. Treatment options are limited, resulting in an extremely high unmet medical need.Tazemetostat was approved in Japan in June 2021 for relapsed or refractory EZH2 gene mutation-positive follicular lymphoma (only when standard treatment is not applicable). For INI1-negative unresectable epithelioid sarcoma that has progressed after chemotherapy, a Phase II investigator-initiated trial of tazemetostat (A Phase II Trial of Tazemetostat for Patients with Unresectable or Metastatic Epithelioid Sarcoma: TAZETTA trial), led by the National Cancer Center Hospital, is currently underway.Eisai identifies oncology as one of its priority areas and strives to develop ground breaking new therapies aimed at curing cancer. We remain committed to meeting the diverse needs of cancer patients worldwide, their families, and healthcare professionals, and to enhancing the benefits delivered to them.*1 A type of histone methyl group elongation enzyme, it is a protein that controls gene expression by methylating the 27th lysine residue of histone H3 (H3K27).*2 One of the proteins that make up the SWI/SNF chromatin complex (a protein complex that modifies chromatinstructure to regulate gene function), it is involved in regulating gene expression.For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202558pdf.pdfMedia Inquiries:Public Relations Department,Eisai Co., Ltd.+81-(0)3-3817-5120 Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com